Results 11 to 20 of about 370,384 (214)

Diisopropyl 1-(4-methoxyphenyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

open access: yesActa Crystallographica Section E, 2011
In the title compound, C28H32N2O7, the 1,4-dihydropyridine ring adopts a flattened boat conformation. The two benzene rings are approximately perpendicular to the dihydropyridine ring, forming dihedral angles of 84.29 (9) and 82.96 (9)
Kamini Kapoor   +4 more
doaj   +2 more sources

Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

open access: yesActa Crystallographica Section E, 2008
The title compound, C18H19NO5, is a product of the Hantzsch reaction of p-phthalaldehyde, methyl acetoacetate, and ammonium acetate. The 1,4-dihydropyridine ring of the molecule adopts a flattened boat conformation.
Fei Teng, Fanpeng Kong, Qingjian Liu
doaj   +2 more sources

1,4-Dihydropyridine activators in the tiamdipine series.

open access: yesEuropean Journal of Pharmacology, 1990
The pharmacologic and radioligand binding properties of 5-nitro analogs of the 1,4-dihydropyridine Ca2+ channel antagonist, tiamdipine (2-(2-aminoethylthio)methyl-3-carbomethoxy-5-carbomethoxy-6-m ethyl-4-(3-nitrophenyl)-1,4-dihydropyridine) and its N ...
Triggle DJ   +2 more
core   +4 more sources

Conformation of 1,4-dihydropyridine - planar or boat-like? [PDF]

open access: yesFEBS Letters, 1988
The geometry of the 1,4-dihydropyridine molecule was completely optimized employing three different ab initio basis sets (6–31 G*, 4–31 G, STO—3G).
R. Cimiraglia   +3 more
core   +3 more sources

Dimethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

open access: yesActa Crystallographica Section E, 2009
In the crystal of the title compound, C11H15NO4, the molecules are linked into sheets by N—H...O and C—H...O hydrogen bonds.
Zhenfeng Zhang   +3 more
doaj   +2 more sources

Synthesis of 1,4-Dihydropyridine Derivatives Under Aqueous Media [PDF]

open access: yesE-Journal of Chemistry, 2010
An environmental friendly synthesis of 1,4-dihydropyridine derivatives was developed by the one-pot reaction of aldehydes, ethyl acetoacetate and ammonia in water under refluxing conditions.
Adeleh Moshtaghi Zonouz   +1 more
doaj   +2 more sources

Chemoenzymatic Synthesis of Enantiopure 1,4-Dihydropyridine Derivates

open access: yesChemInform, 2004
1,4-Dihydropyridines possess a broad range of biological activities, such as the ability to control the influx of calcium into cells, as well as neuroprotective, antineuro-degenerative, cognition and memory enhancing, anti-inflammatory, antiviral and ...
Sobolev, A.   +3 more
core   +3 more sources

Antischistosomal Activity of 1,4-Dihydropyridines

open access: yesDrugs and Drug Candidates
Background/Objectives: Recent reports have demonstrated the antiparasitic activity of 1,4-dihydropyridine (1,4-DHPs). This study aimed to assess the in vitro antischistosomal activity of 24 1,4-DHPs against Schistosoma mansoni adult worms.
Thaís A. S. Oliveira   +5 more
doaj   +2 more sources

Synthesis and in vitro Evaluation of the Antimycobacterial Activity of N-aryl-1,4-dihydropyridine-3,5-dicarboxamides [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2012
Dihydropyridines (DHPs) with carboxamides in the 3 and 5 positions show anti-tuberculosis activity. The purpose of the present study was to synthesize new DHPs that would possibly possess anti-tuberculosis activity.
F. Mohammadpour
doaj   +2 more sources

4-(3,5-Dibromo-4-hydroxyphenyl)-3-butoxycarbonyl-5-ethoxycarbonyl-2-methyl-6-phenyl-1,4-dihydropyridine

open access: yesMolbank, 2011
One-pot two-step Hantzsch synthesis of 4-(3,5-dibromo-4-hydroxyphenyl)-3- butoxycarbonyl-5-ethoxycarbonyl-2-methyl-6-phenyl-1,4-dihydropyridine under solvent- and catalyst-free conditions promoted with microwave irradiation is presented.
Zhen Wang, Qingjian Liu
doaj   +2 more sources

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