Results 41 to 50 of about 8,139 (202)

Hantzsch Synthesis of 2,6-Dimethyl-3,5-dimethoxycarbonyl-4-(o-methoxyphenyl)-1,4-dihydropyridine; a Novel Cyclisation Leading to an Unusual Formation of 1-Amino-2-methoxycarbonyl-3,5-bis(o-methoxyphenyl)-4-oxa-cyclohexan-1-ene

Molecules, 2007
Hantzsch condensation of two equivalents of methyl-3-aminocrotonate with (m-and p)-methoxybenzaldehyde afforded the expected products 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(m-methoxyphenyl)-1,4-dihydropyridine and 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(p ...
Vladimir Vinković, Ivica Cepanec, Mladen Litvić, Mirela Filipan-Litvić   +3 more
doaj   +1 more source

1,1′-{[3,5-Bis(dodecyloxycarbonyl)-4-(naphthalen-2-yl)-1,4-dihydropyridine-2,6-diyl]bis(methylene)}bis{4-[(E)-2-(naphthalen-2-yl)vinyl]pyridin-1-ium}dibromide

Molbank, 2022
Synthesis of a double-charged cationic amphiphilic 1,4-dihydropyridine derivative with dodecyl ester groups at positions 3 and 5 of the 1,4-DHP ring was performed starting from Hantzsch type cyclization of dodecyl acetoacetate, 2-naphthaldehyde and ...
Martins Rucins, Martins Kaukulis, Aiva Plotniece, Karlis Pajuste, Nadiia Pikun, Arkadij Sobolev   +5 more
doaj   +1 more source

Diethyl 2,6-Dimethyl-4-(naphthalen-1-yl)-1,4-Dihydropyridine-3,5-Dicarboxylate [PDF]

, 2016
In the title compound, C23H25NO4, the 1,4-dihydropyridine ring adopts a flattened boat conformation. The naphthalene ring system forms a dihedral angle of 88.59 (6)° with the pyridine ring.
Noor Shahina Begum, ., Prasad, N.L.
core   +1 more source

Chemoenzymatic Synthesis of Enantiopure 1,4‐Dihydropyridine Derivatives

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Sobolev, A., Franssen, M.C.R., Duburs, G., de Groot, Æ.   +3 more
openaire   +2 more sources

Synthesis and biological evaluation of 1,2,4-triazoles and 1,3,4-oxadiazoles derivatives linked to 1,4-dihydropyridines scaffold

Acta Chimica Slovenica, 2017
A series of diethyl-2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate derivative coupled to 1,3,4-oxadiazole-5-thiones and 1,2,4-triazole-5-thiones moieties at C2,C6 positions of 1,4-dihydropyridine ring system was prepared.
Maghsoud Ziaie, Karim Akbaridilmaghani, Amir Tukmechi   +2 more
doaj   +1 more source

The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio, René Slot Bitsch, Karl Anker Jørgensen   +2 more
wiley   +2 more sources

Contraction force versus action potential duration of cardiomyocytes: which methodology is more informative for selection of effective 1,4-dihydropyridine compounds in experimental research?

Acta Medica Lituanica, 2015
Background. Identification of activity properties of new synthesized compounds is important to help choose the adequate research methodology. The goal of this experimental research was to determine the relationship between the chemical structure of 25 ...
Vygantas Barsys, Vida Garalienė, Gediminas Urbonas   +2 more
doaj   +1 more source

Synthesis of novel 1,4-Dihydropyridine derivative labeled with Carbon-14 [PDF]

مجله علوم و فنون هسته‌ای, 2019
Synthesis of 14C-labeled organic compounds is being required by the medical, pharmaceutical, agricultural, industrial, and research centers. The Carbon-14 is essential for the tracking and recognizing the mechanism and performance of the synthesized ...
M.A Ahmadi Faghih, M.H Mosslemin, G Shirvani, M Javaheri   +3 more
doaj   +1 more source

Dimethyl 4-(3,4-dimethoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Acta Crystallographica Section E, 2010
In the title compound, C19H23NO6, the 1,4-dihydropyridine ring is twisted slightly from planarity, with a maximum deviation of 0.101 (1) Å, and adopts a very flattened boat conformation.
Tara Shahani, Hoong-Kun Fun, B. Palakshi Reddy, V. Vijayakumar, S. Sarveswari   +4 more
doaj   +1 more source

TRPA1 channels: Novel targets of 1,4-dihydropyridines [PDF]

Channels, 2008
Transient receptor potential type A1 (TRPA1) channels are cation permeable channels activated by irritant chemicals and pungent natural compounds. Their location in peptidergic sensory terminals innervating the skin and blood vessels makes them important effectors of vasodilator responses of neural origin.
Fajardo, Otto, Meseguer, Víctor M., Belmonte, Carlos, Viana, Félix   +3 more
openaire   +3 more sources