Results 1 to 10 of about 19,079 (197)

Comparison between 1,2-Dihydropyridine and 1,4-Dihydropyridine on Hydride-Donating Ability and Activity

Molecules, 2022
In this paper, detailed comparisons of the driving force in thermodynamics and intrinsic force in the kinetics of 1,2-dihydropyridine and 1,4-dihydropyridine isomers of PNAH, HEH, and PYH in hydride transfer reactions are made. For 1,2-PNAH and 1,4-PNAH, the values of the thermodynamic driving forces, kinetic intrinsic barriers, and thermo-kinetic ...
Jin-Ye Zhang, Xiao-Qing Zhu
exaly   +4 more sources

Green synthesis, molecular docking and anticancer activity of novel 1,4-dihydropyridine-3,5-Dicarbohydrazones under grind-stone chemistry

Green Chemistry Letters and Reviews, 2020
The reaction of 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarbohydrazide with variety of carbonyl compounds such as substituted benzaldehydes, cycloalkanones and hetero-cyclic ketones under grinding method under catalyst- and solvent-free ...
Sobhi M Gomha, Zeinab A Muhammad, Hassan M Abdel-Aziz   +2 more
exaly   +2 more sources

Catalytic Enantioselective Diboration of 1,2-Dihydropyridines. [PDF]

Angew Chem Int Ed Engl
Abstract Dihydropyridines undergo enantioselective 1,4‐diboration in the presence of a chiral Pt‐based catalyst. The resulting diboryl piperidines can undergo diverse stereospecific cross‐couplings, allowing the construction of an array of different substituted chiral piperidines.
Liang H, Morken JP.
europepmc   +4 more sources

Dihydropyridine calcium blockers do not interfere with non-rapid eye movement sleep

Frontiers in Neuroscience, 2022
Non-rapid eye movement (NREM) sleep is tightly homeostatically regulated and essential for survival. In the electroencephalogram (EEG), oscillations in the delta (0.5–4 Hz) range are prominent during NREM sleep. These delta oscillations are, to date, the
GoEun Han, Sumire Matsumoto, Javier Diaz, Robert W. Greene, Robert W. Greene, Kaspar E. Vogt   +5 more
doaj   +1 more source

A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au³⁺ Residue in Gold Nanoparticle Solution

Sensors, 2022
Novel dihydroquinoline derivatives (DHP and DHP-OH) were synthesized in one pot via a tandem trimerization-cyclization of methylpropiolate. DHP and DHP-OH possess strong blue fluorescence with high quantum efficiencies over 0.70 in aqueous media.
Waroton Paisuwan, Mongkol Sukwattanasinitt, Mamoru Tobisu, Anawat Ajavakom   +3 more
doaj   +1 more source

Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2021
An efficient green approach for the synthesis of 9-heteroaryl-acridine-1,8-dione derivatives (3a-f) was accomplished via reactions of dimedone (1) with various heteroaromatic aldehydes (2a-f) and ammonium acetate through one-pot multicomponent reactions ...
Mehtap Özgür, Duygu Bayramoğlu
doaj   +1 more source

1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori

Frontiers in Microbiology, 2022
The increasing occurrence of multidrug-resistant strains of the gastric carcinogenic bacterium Helicobacter pylori threatens the efficacy of current eradication therapies.
Andrés González, Andrés González, Andrés González, Andrés González, Javier Casado, Javier Casado, Miyase Gözde Gündüz, Brisa Santos, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Cristina Sarasa-Buisan, Cristina Sarasa-Buisan, María F. Fillat, María F. Fillat, Milagrosa Montes, Milagrosa Montes, Elena Piazuelo, Elena Piazuelo, Elena Piazuelo, Ángel Lanas, Ángel Lanas, Ángel Lanas, Ángel Lanas   +24 more
doaj   +1 more source

Amlodipine Overdose: Is High Dose Insulin Ready for Prime Time

Hearts, 2022
Overdose of amlodipine, a dihydropyridine calcium channel blocker (CCB), is distinguished from other CCBs due to longer plasma half-life of 30 to 58 h.
Mary Jo S. Farmer, Anisha Contractor, Joshua Allgaier   +2 more
doaj   +1 more source

Dihydropyridine Enhances the Antioxidant Capacities of Lactating Dairy Cows under Heat Stress Condition

Animals, 2020
Heat stress (HS), a nonspecific response to environmental heat, can seriously affect dairy cow health. Feed additives may alleviate HS in dairy cows by improving rumen fermentation efficacy, stimulating feed consumption, enhancing vasodilation, and/or ...
Meng-Fei Yu, Xin-Mao Zhao, Hang Cai, Jian-Ming Yi, Guo-Hua Hua   +4 more
doaj   +1 more source

Development of a Rapid Mass Spectrometric Determination of AMP and Cyclic AMP for PDE3 Activity Study: Application and Computational Analysis for Evaluating the Effect of a Novel 2-oxo-1,2-dihydropyridine-3-carbonitrile Derivative as PDE-3 Inhibitor

Molecules, 2020
A simple, quick, easy and cheap tandem mass spectrometry (MS/MS) method for the determination of adenosine monophosphate (AMP) and cyclic adenosine monophosphate (cAMP) has been newly developed.
Ilaria Cicalini, Barbara De Filippis, Nicola Gambacorta, Antonio Di Michele, Silvia Valentinuzzi, Alessandra Ammazzalorso, Alice Della Valle, Rosa Amoroso, Orazio Nicolotti, Piero Del Boccio, Letizia Giampietro   +10 more
doaj   +1 more source