Results 31 to 40 of about 36,465 (190)

Effect of Dihydropyridine Calcium Channel Blocker on Mortality of Hypertension Patients With Moderate-Severe Pulmonary Acute Respiratory Distress Syndrome: A Multicenter Retrospective Observational Cohort Study

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. The aim was to evaluate the effect of dihydropyridine calcium channel blocker on the prognosis for moderate-severe pulmonary acute respiratory distress syndrome in hypertension patients. DESIGN:.
Fengyuan Li, MD   +9 more
doaj   +1 more source

The roles of the subunits in the function of the calcium channel [PDF]

open access: yes, 1991
Dihydropyridine-sensitive voltage-dependent L-type calcium channels are critical to excitation-secretion and excitation-contraction coupling. The channel molecule is a complex of the main, pore-forming subunit alpha 1 and four additional subunits: alpha ...
Biel, Martin   +5 more
core   +1 more source

Heart rate variability and target organ damage in hypertensive patients [PDF]

open access: yes, 2012
Background: We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).
2003 European Society of Hypertension   +56 more
core   +4 more sources

Oxygen-Induced Dimerization of Alkyl-Manganese(II) 2,6-Bisiminopyridine Complexes: Selective Synthesis of a New Ditopic NNN-Pincer Ligand [PDF]

open access: yes, 2016
The outcome of the reaction of manganese(II) dialkyls with 2,6-bisiminopyridine (BIP) ligands is dramatically altered by the presence of very small amounts of oxygen (< 0.5 mol %), leading to binuclear species.
Cámpora Pérez, Juan   +5 more
core   +4 more sources

Tetrodotoxin as a Tool to Elucidate Sensory Transduction Mechanisms: The Case for the Arterial Chemoreceptors of the Carotid Body

open access: yesMarine Drugs, 2011
Carotid bodies (CBs) are secondary sensory receptors in which the sensing elements, chemoreceptor cells, are activated by decreases in arterial PO2 (hypoxic hypoxia).
Constancio Gonzalez   +3 more
doaj   +1 more source

Synthesis, Absorption, Distribution, Metabolism, Excretion, Toxicology (ADMET) and molecular docking studies of some pyridin-2(1H)-one derived from a Apocynin in Thi-Qar Governorate

open access: yesمجلة علوم ذي قار, 2023
The present study includes synthesized of some pyridin-2(1H)- one of 1-(4-hydroxy-3-methoxyphenyl) ethan-1-one. The [ 6-(4-hydroxy-3-methoxyphenyl) - 4 - (4-methoxyphenyl) - 2 - oxo-1,2-dihydropyridine - 3- carbonitrile, 4 - (4-bromophenyl) - 6 -(4 ...
Entedhar Thejeel, Athraa Hameed Mekky
doaj   +1 more source

Diethyl 4-(4-chloro-2-propyl-1H-imidazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate monohydrate

open access: yesIUCrData, 2018
In the title hydrate, C19H26ClN3O4·H2O, the imidazole ring is nearly perpendicular [dihedral angle = 89.5 (1)°] to the dihydropyridine moiety. The propyl and one of the ethyl groups are disordered over two resolved sets of sites [occupancy factors 0.524 (
Kedila Rasheeda   +5 more
doaj   +1 more source

Selection of medication in hospitalised elderly patients with Angina Pectoris [PDF]

open access: yes, 2004
Objective: To evaluate medication changes in hospitalised elderly patients diagnosed with angina pectoris and to compare the selection of medication with evidence-based treatment guidelines. Design: Review of medical notes and patient interview. Setting:
Cacciottolo, Joseph M.   +2 more
core  

Fragment Coupling and the Construction of Quaternary Carbons Using Tertiary Radicals Generated From tert-Alkyl N-Phthalimidoyl Oxalates By Visible-Light Photocatalysis. [PDF]

open access: yes, 2015
The coupling of tertiary carbon radicals with alkene acceptors is an underdeveloped strategy for uniting complex carbon fragments and forming new quaternary carbons.
Lackner, Gregory L   +3 more
core   +3 more sources

General Synthesis of Substituted 1,2-Dihydropyridines [PDF]

open access: yesThe Journal of Organic Chemistry, 2014
A general and practical metal-free protocol for the synthesis of 1,2-dihydropyridines with wide structural/functional diversity at the ring and featuring mono, double, or spiro substitution at the sp(3) position is described. The protocol entails a microwave-assisted domino reaction of a propargyl vinyl ether (secondary or tertiary) and a primary amine
Tejedor, David   +3 more
openaire   +3 more sources

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