Results 31 to 40 of about 26,691 (223)

Synthesis, characterization and Theoretical study of some 2-Oxopyridine Carbonitrile derivatives that contain tetrazole ring and evaluation of their Biological activity

مجلة علوم ذي قار, 2023
A series of 2-oxo-6-[4-(1H-tetrazol-1-yl) phenyl-1,2-dihydropyridine-3-carbonitrile 3,4-dimethoxyphenyl)-2-oxo-6-4-(1H-tetrazol-1-yl) phenyl]-1,2-dihydropyridine-3-carbonitrile and 2-oxo-6-[4-(1H-tetrazol-1-yl) phenyl]-4-(thiophen-2-yl)- 1,2 ...
Athraa Hamed Mekky, Meinaa Jaber Dalal, Athraa G. Sager, Noor Abd Alkhudhur Salmn , Abbas Talib Abd Ali, M.R. Jayapal   +5 more
doaj   +1 more source

3-Methyl 5-{3-[(4-Methylbenzenesulfonyl)oxy]propyl} 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Molbank, 2022
The 1,4-dihydropyridine is a ubiquitous scaffold employed not only in medicinal chemistry but also in organic synthesis, given its ability to act as a hydrogen transfer reagent, thus emulating NAD(P)H reducing agents.
Carlotta Borgarelli, Stijn Lenaers, Wim M. De Borggraeve, Ermal Ismalaj   +3 more
doaj   +1 more source

Synthesis and Utility of Dihydropyridine Boronic Esters [PDF]

, 2016
When activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine ...
Santanu Panda, Joseph M. Ready, Nguyen, Q Nhu, Ready, Joseph M, Tantillo, Dean J, Coffin, Aaron, Aaron Coffin, Q. Nhu Nguyen, Dean J. Tantillo, Panda, Santanu   +9 more
core   +1 more source

HIVAN and medication use in chronic dialysis patients in the United States: analysis of the USRDS DMMS Wave 2 study

BMC Nephrology, 2003
Background The use and possible effects of factors known to improve outcomes in patients with human immunodeficiency virus associated nephropathy (HIVAN), namely of angiotensin converting enzyme inhibitors (ACE) and antiretroviral therapy, has not been ...
Agodoa Lawrence Y, Trespalacios Fernando C, Abbott Kevin C, Ahuja Tejinder S   +3 more
doaj   +1 more source

Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth

Journal of Indian Society of Periodontology, 2019
Drug-induced gingival overgrowth is a frequently observed adverse effect of antihypertensive drug calcium channel blockers (CCBs). Gingival enlargements are more common with the dihydropyridine class of CCBs.
Sameera Gopinath, Vadakkedath Venugopal Harishkumar, Vediyera Chandroth Santhosh, Sreekanth Puthalath   +3 more
doaj   +1 more source

Dihydropyridine-Based Multicomponent Reactions. Efficient Entry into New Tetrahydroquinoline Systems through Lewis Acid-Catalyzed Formal [4 + 2] Cycloadditions

, 2016
The three-component reaction of dihydropyridines, aldehydes, and p-methylaniline efficiently forms highly substituted tetrahydroquinolines in a stereoselective manner through a Lewis acid-catalyzed formal [4 + 2] cycloaddition. InCl3 and Sc(OTf)3 are the
José Luis Díaz (2516782), Inés Carranco (3027048), Rodolfo Lavilla (1892905), M. Carmen Bernabeu (3066654)   +3 more
core   +1 more source

Synthesis and Aromatization of Hantzsch 1,4-Dihydropyridines under Microwave Irradiation. An Overview

Molecules, 2003
Domestic microwave ovens as well as laboratory reactors have been successfully employed to prepare dialkyl 1,4-dihydropyridine-3,5-dicarboxylates and to induce the synthesis of the corresponding aromatic derivatives.
Annie Mayence, Jean Jacques Vanden Eynde
doaj   +1 more source

Effect of Dihydropyridine Calcium Channel Blocker on Mortality of Hypertension Patients With Moderate-Severe Pulmonary Acute Respiratory Distress Syndrome: A Multicenter Retrospective Observational Cohort Study

Critical Care Explorations, 2021
OBJECTIVES:. The aim was to evaluate the effect of dihydropyridine calcium channel blocker on the prognosis for moderate-severe pulmonary acute respiratory distress syndrome in hypertension patients. DESIGN:.
Fengyuan Li, MD, Chang Gao, MD, Jiahao Chen, MD, Ling Yang, MD, Shiqi Guo, MD, Dongmei Jin, MD, Xiaoting Lu, MD, Yin Sheng, MD, Xiaoxia Ji, MD, Qiang Guo, MD   +9 more
doaj   +1 more source

Synthesis and in vitro Evaluation of the Antimycobacterial Activity of N-aryl-1,4-dihydropyridine-3,5-dicarboxamides [PDF]

Journal of Sciences, Islamic Republic of Iran, 2012
Dihydropyridines (DHPs) with carboxamides in the 3 and 5 positions show anti-tuberculosis activity. The purpose of the present study was to synthesize new DHPs that would possibly possess anti-tuberculosis activity.
F. Mohammadpour
doaj  

Antibacterial and antileishmanial activity of 1,4-dihydropyridine derivatives [PDF]

We have synthesized twenty-three 1,4-dihydropyridine derivatives (1,4-DHPs) by using a microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their antibacterial activity against a representative panel of cariogenic bacteria and their ...
Thaís, Oliveira, Andreia, Oliveira, Antônio, Crotti, Carlos, Martins, Jackson, Silva, Nagela, Silva, Paulo, Félix, Lizandra, Magalhães   +7 more
core   +2 more sources