Results 51 to 60 of about 7,944 (148)
, 2016 Some novel dihydropyridine derivatives, viz., 4-(4-hydroxy-3-methoxyphenyl)-6-(2-hydroxyphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile, 4-(4-hydroxy-3-methoxyphenyl)-6-(4-hydroxyphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile, 6-(4-chlorophenyl)-4-(4 ...
Rahul M. Talaviya (2544049) +1 more
core +1 more source
European Journal of Organic Chemistry, EarlyView.An efficient gold‐catalyzed intramolecular cyclization of indole‐tethered alkynes using AgNTf2 as an additive has been developed, which provides bioactive exocyclic alkenyl tetrahydrocarbazoles with up to 85% yield. Control experiments and DFT studies indicate that the reaction proceeds via a 6‐exo‐dig cyclization pathway, with gold acetylide complexes
Haibo Mei +4 more
wiley +1 more source
Chemistry Proceedings, 2023 The reaction of 1,6-diamino-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles, which are easily available through the reaction of cyanoacetohydrazide with arylmethylene malononitriles, with ninhydrin leads to the formation of novel dihydroindeno[1,2-e]pyrido[
Alexei A. Dolganov +2 more
doaj +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Affinity Purification of Antibodies Specific for 1,4-Dihydropyridine Ca 2+ Channel Blockers [PDF]
, 2020 High-affinity antibodies specific for the 1,4-dihydropyridine Ca 2+ channel blockers have been produced in sheep and affinity purified using a dihydropyridine-Sepharose affinity column.
Kevin P Campbell, Alan H Sharp
core
Therapeutic‐dose verapamil‐induced cardiogenic shock in an older patient: a case report
Journal of Pharmacy Practice and Research, EarlyView.Abstract Background Calcium channel blocker (CCB) toxicity most commonly follows deliberate overdose. However, severe toxicity at therapeutic doses may occur in susceptible individuals. Severe CCB toxicity often presents with clinical features of bradycardia, hypotension, hyperglycaemia, and lactic acidosis.
Christopher Thuring +3 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source
Spiro compounds with fragments of 4-azafluorene-[indeno(2,3-e)-1,2-dihydropyridine] and pyrazoline
, 2020 9-Phenacylidene-4-azafluorene and 9-bromo-9-(α-bromophenacyl)-4-azafluorene have been used in the synthesis of spiro compounds with fragments of substituted pyrazolines.
Mikhailova N.M. +2 more
core +1 more source
Role of Alkaline-Earth Metal-Catalyst: A Theoretical Study of Pyridines Hydroboration
Frontiers in Chemistry, 2019 Density functional theory (DFT) calculations have been performed to investigate the mechanism of alkaline-earth-metal-catalyzed hydroboration of pyridines with borane.
Yuanyuan Li +10 more
doaj +1 more source
Synthesis of novel 1,4-Dihydropyridine derivative labeled with Carbon-14 [PDF]
مجله علوم و فنون هستهای, 2019 Synthesis of 14C-labeled organic compounds is being required by the medical, pharmaceutical, agricultural, industrial, and research centers. The Carbon-14 is essential for the tracking and recognizing the mechanism and performance of the synthesized ...
M.A Ahmadi Faghih +3 more
doaj +1 more source