Results 51 to 60 of about 36,465 (190)

Synthesis of novel 1,4-Dihydropyridine derivative labeled with Carbon-14 [PDF]

open access: yesمجله علوم و فنون هسته‌ای, 2019
Synthesis of 14C-labeled organic compounds is being required by the medical, pharmaceutical, agricultural, industrial, and research centers. The Carbon-14 is essential for the tracking and recognizing the mechanism and performance of the synthesized ...
M.A Ahmadi Faghih   +3 more
doaj   +1 more source

Fast microwave-assisted oxidation of 1,4-dihydropyridines with FeCl 3.SiO 2 [PDF]

open access: yes, 2005
Pyridine derivatives are easily obtained in high yields by microwave-promoted rapid oxidation of the corresponding 1,4-dihydropyridines with ferric chloride hexahydrate and silica gel under solvent-free ...
Alaee, E.   +4 more
core   +1 more source

Diisopropyl 1-(4-methoxyphenyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

open access: yesActa Crystallographica Section E, 2011
In the title compound, C28H32N2O7, the 1,4-dihydropyridine ring adopts a flattened boat conformation. The two benzene rings are approximately perpendicular to the dihydropyridine ring, forming dihedral angles of 84.29 (9) and 82.96 (9)
Kamini Kapoor   +4 more
doaj   +1 more source

Effect of New Derivatives of Dihydropyridine on Rat Ileal Smooth Muscle in Vitro [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2003
In this research we evaluated the calcium channel antagonist activity of various diester analohues of nifedipine on rat ileal smooth muscle.in these analogues,the orthophenyl group at position 4 was replaced by 1 methyl 2-meythylsulfonyl or methylthio 5 ...
M Rezvanipour   +5 more
doaj  

10-Benzyl-9-(4-ethoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione

open access: yesActa Crystallographica Section E, 2012
In the title compound, C32H37NO3, the central dihydropyridine ring adopts a nearly planar flattened-boat conformation, whereas both cyclohexenone rings adopt half-chair conformations.
V. Sughanya, N. Sureshbabu
doaj   +1 more source

Clinical Advantages of Lipophilic Dihydropyridines

open access: yesBlood Pressure, 1998
Lipophilic dihydropyridines have many theoretical and practical clinical advantages owing to their long permanence at the cell membrane. They have a greater chance of smoothly and permanently reducing blood pressure over 24 h than other dihydropyridines, a feature that may have positive prognostic implications since 24-h blood pressure is more closely ...
G, Mancia, S, Omboni, A, Zanchetti
openaire   +2 more sources

1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone

open access: yesActa Crystallographica Section E, 2011
In the title compound, C17H17Cl2NO2, the central 1,4-dihydropyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydropyridine ring at positions 3 and 5 have synperiplanar (cis) or antiperiplanar (trans) conformations ...
J. Kalyana Sundar   +5 more
doaj   +1 more source

Tissue-specific expression of calcium channels [PDF]

open access: yes, 1993
The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Biel   +59 more
core   +1 more source

DIHYDROPYRIDINE CALCIUM ANTAGONISTS: DATA OF EVIDENCE BASED MEDICINE AND RECOM-MENDATIONS ON PRACTICAL USE

open access: yesРациональная фармакотерапия в кардиологии, 2015
The classification of calcium antagonists is presented. There were considered the results of large randomized trials, which were devoted to study of influence of dihydropyridine calcium antagonists on the risk of cardiovascular complications.
S. Y. Martsevich
doaj   +3 more sources

Bromination and Diazo-Coupling of Pyridinethiones; Microwave Assisted Synthesis of Isothiazolopyridine, Pyridothiazine and Pyridothiazepines

open access: yesMolecules, 2012
Isothiazolopyridines, pyridothiazines and pyridothiazepines are important compounds that possess valuable biological activities. This paper reports on the synthesis of these compounds using both conventional chemical methods and modern microwave ...
Ayman M. S. Youssef   +2 more
doaj   +1 more source

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