Results 41 to 50 of about 19,079 (197)
European Journal of Organic Chemistry, EarlyView.The intramolecular nitrile oxide olefin [3 + 2]‐cycloaddition offers a reliable entry toward 2‐aza‐bicyclo[4.3.0]‐nonanes, a substructure found in several bioactive piperidine alkaloids. The required oxime precursors were prepared in non‐racemic form by Ir‐catalyzed asymmetric allylation and ring‐closing metathesis.
Alicia Köcher +5 more
wiley +1 more source
Role of Alkaline-Earth Metal-Catalyst: A Theoretical Study of Pyridines Hydroboration
Frontiers in Chemistry, 2019 Density functional theory (DFT) calculations have been performed to investigate the mechanism of alkaline-earth-metal-catalyzed hydroboration of pyridines with borane.
Yuanyuan Li +10 more
doaj +1 more source
Synthesis of novel 1,4-Dihydropyridine derivative labeled with Carbon-14 [PDF]
مجله علوم و فنون هستهای, 2019 Synthesis of 14C-labeled organic compounds is being required by the medical, pharmaceutical, agricultural, industrial, and research centers. The Carbon-14 is essential for the tracking and recognizing the mechanism and performance of the synthesized ...
M.A Ahmadi Faghih +3 more
doaj +1 more source
Gold(I)‐Mediated Reactivity of Allenes With Mesoionic Nucleophiles: A Computational Exploration
European Journal of Organic Chemistry, EarlyView.The regioselective gold(I)‐mediated reactivity of allenes with mesoionic nucleophiles has been evaluated through computational analysis of the mechanisms involved. Instead of typical (3 + 2) pathways, sydnones and münchnones favour the formal (3 + 3) cyclizations affording substituted dihydropyridines.
Eduardo Garcia‐Padilla, Feliu Maseras
wiley +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard +9 more
wiley +1 more source
Smart Molecules, EarlyView.This review elucidates the photophysical mechanisms of cellulose‐based room temperature phosphorescent materials and systematically outlines their construction strategies, such as cluster emission center engineering. This article demonstrates their applications in fields like information encryption and bioimaging, and looks ahead to the core challenges
Shasha Wu +10 more
wiley +1 more source
Diisopropyl 1-(4-methoxyphenyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Acta Crystallographica Section E, 2011 In the title compound, C28H32N2O7, the 1,4-dihydropyridine ring adopts a flattened boat conformation. The two benzene rings are approximately perpendicular to the dihydropyridine ring, forming dihedral angles of 84.29 (9) and 82.96 (9)
Kamini Kapoor +4 more
doaj +1 more source
The Chemical Record, EarlyView.This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Effect of New Derivatives of Dihydropyridine on Rat Ileal Smooth Muscle in Vitro [PDF]
Journal of Kerman University of Medical Sciences, 2003 In this research we evaluated the calcium channel antagonist activity of various diester analohues of nifedipine on rat ileal smooth muscle.in these analogues,the orthophenyl group at position 4 was replaced by 1 methyl 2-meythylsulfonyl or methylthio 5 ...
M Rezvanipour +5 more
doaj