Results 21 to 30 of about 26,691 (223)

Tissue-specific expression of calcium channels [PDF]

, 1993
The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Flockerzi, Veit, Biel, Martin, Hullin, Roger, Hofmann, Franz   +3 more
core   +1 more source

Clusterization-Triggered Color-Tunable Room-Temperature Phosphorescence from 1,4-Dihydropyridine-Based Polymers

, 2021
A series of poly­(1,4-dihydropyridine)­s (PDHPs) were successfully synthesized via one-pot metal-free multicomponent polymerization of diacetylenic esters, benzaldehyde, and aniline derivatives.
Lianwei Li, Siqi Huang (2558686), Yuping Dong, Siqi Huang, Yue Ren (1311615), Shuai Guo, Nairong Hao (6270215), Lichao Dong, Jianbing Shi (1471882), Zhengxu Cai (1419718), Yue Ren, Jianbing Shi, Lianwei Li (1658128), Wenbo Dai, Bin Tong, Wenbo Dai (7115471), Lichao Dong (1471879), Yuping Dong (1471885), Zhengxu Cai, Bin Tong (1471891), Nairong Hao, Shuai Guo (1353816)   +21 more
core   +1 more source

Effects of dietary dihydropyridine supplementation on growth performance and lipid metabolism of broiler chickens

Czech Journal of Animal Science, 2010
An experiment was conducted to investigate the effects of dihydropyridine supplementation on growth performance and lipid metabolism of broilers. A total of 480 one-day-old female Arbor Acres broiler chicks were randomly divided into four groups, each ...
Z.Y. Niu, F.Z. Liu, Y.N. Min, W.C. Li
doaj   +1 more source

Cardioprotective Effect against Ischemia–Reperfusion Injury of PAK-200, a Dihydropyridine Analog with an Inhibitory Effect on Cl⁻ but Not Ca²⁺ Current

Biomolecules, 2023
We examined the effects of a dihydropyridine analog, PAK-200, on guinea pig myocardium during experimental ischemia and reperfusion. In isolated ventricular cardiomyocytes, PAK-200 (1 μM) had no effect on the basal peak inward and steady-state currents ...
Iyuki Namekata, Miku Tamura, Jyunya Kase, Shogo Hamaguchi, Hikaru Tanaka   +4 more
doaj   +1 more source

Immunochemical detection of a lipofuscin-like fluorophore derived from malondialdehyde and lysine

Journal of Lipid Research, 2001
The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of postmitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and
Satoshi Yamada, Shigenori Kumazawa, Takeshi Ishii, Tsutomu Nakayama, Koichi Itakura, Noriyuki Shibata, Makio Kobayashi, Kensuke Sakai, Toshihiko Osawa, Koji Uchida   +9 more
doaj   +1 more source

Alterations in dihydropyridine receptors in dystrophin-deficient cardiac muscle [PDF]

, 2006
The deficiency of dystrophin, a critical membrane stabilizing protein, in the mdx mouse causes an elevation in intracellular calcium in myocytes. One mechanism that could elicit increases in intracellular calcium is enhanced influx via the L-type calcium
Lu, Sai, Watson, M, Woolf, Peter James, Hoey, AJ, Cornford-Nairn, R, Holroyd, SM, Hoey, Andrew, Woolf, PJ, Cornford-Nairn, Renee, Hoey, Andrew J., Xiao, Xiao-Hui, Woolf, Peter J., Xiao, XH, Holroyd, Sean M., Watson, Michael, Cornford-Nairn, Renee A., Brown, Lindsay, Holroyd, Sean, Brown, L   +18 more
core   +1 more source

Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol

Applied Sciences, 2012
This article describes one-pot synthesis of new fluorinated hexahydroquinoline derivatives via unsymmetric Hantzsch reaction involving 5-trifluoromethyl-1,3-cyclohexanedione, aldehydes, acetoacetate ester, and ammonium acetate in trifluoroethanol (TFE ...
Cosmas O. Okoro, Mumiye A. Ogunwale, Tasneem Siddiquee   +2 more
doaj   +1 more source

Recent Progresses in the Catalytic Stereoselective Dearomatization of Pyridines

Molecules, 2023
1,2- and 1,4-dihydropyridines and N-substituted 2-pyridones are very important structural motifs due to their synthetic versatility and vast presence in a variety of alkaloids and bioactive molecules.
Lucrezia Margherita Comparini, Mauro Pineschi   +1 more
doaj   +1 more source

Heterogeneity of calcium channels from a purified dihydropyridine receptor preparation. [PDF]

, 1987
Dihydropyridine receptors were purified from rabbit skeletal muscle transverse tubule membranes and incorporated into planar lipid bilayers. Calcium channels from both the purified dihydropyridine receptor preparation and the intact transverse tubule ...
Talvenheimo, J. A., Nelson, M. T.; id_orcid, Worley, J. F.   +2 more
core   +7 more sources

Experimental, Molecular Docking and Molecular Dynamics Investigation on Newly Synthesized Diethyl 4-(Anthracen-9-yl)-2,6-Dimethyl-1,4-Dihydropyridine-3,5-Dicarboxylate

, 2022
The novel compound diethyl 4-(anthracen-9-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (DHPA) was synthesized via the Hantzsch method. The synthesized compound was studied through FT-IR, FT-Raman, UV-Vis and NMR studies were compared with ...
Velraj G (13218114), Karthick R (13218111), Karuppusamy A (13218117), Karthikeyan S (13218120)   +3 more
core   +1 more source