Results 61 to 70 of about 4,494 (179)

Catalytic Asymmetric Synthesis of Both Enantiomers of 4‑Substituted 1,4-Dihydropyridines with the Use of Bifunctional Thiourea-Ammonium Salts Bearing Different Counterions

Molecules, 2010
Organoammonium salts composed of a Brønsted acid and an anilinothiourea promoted the Michael addition of β-keto esters and α,β-unsaturated aldehydes in the presence of primary amines to give functionalized 1,4-dihydropyridines enantioselectively.
Kohzo Yoshida, Tsubasa Inokuma, Kiyosei Takasu, Yoshiji Takemoto   +3 more
doaj   +1 more source

Crystal structure of ethyl 2-[9-(5-bromo-2-hydroxyphenyl)-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydroacridin-10-yl]acetate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C23H24BrNO5, the central 1,4-dihydropyridine ring of the 1,2,3,4,5,6,7,8,9,10-decahydroacridine ring system adopts a half-chair conformation. The two cyclohexene rings fused to the central ring both have a twisted-boat conformation.
Shaaban K. Mohamed, Mehmet Akkurt, Jerry P. Jasinski, Antar A. Abdelhamid, Asmaa H. Tamam, Mustafa R. Albayati   +5 more
doaj   +1 more source

4-(3,5-Dibromo-4-hydroxyphenyl)-3-butoxycarbonyl-5-ethoxycarbonyl-2-methyl-6-phenyl-1,4-dihydropyridine

Molbank, 2011
One-pot two-step Hantzsch synthesis of 4-(3,5-dibromo-4-hydroxyphenyl)-3- butoxycarbonyl-5-ethoxycarbonyl-2-methyl-6-phenyl-1,4-dihydropyridine under solvent- and catalyst-free conditions promoted with microwave irradiation is presented.
Zhen Wang, Qingjian Liu
doaj   +1 more source

Synthesis of 1,4-Dihydropyridine Derivatives Under Aqueous Media

E-Journal of Chemistry, 2010
An environmental friendly synthesis of 1,4-dihydropyridine derivatives was developed by the one-pot reaction of aldehydes, ethyl acetoacetate and ammonia in water under refluxing conditions.
Adeleh Moshtaghi Zonouz, Nahid Sahranavard   +1 more
doaj   +1 more source

Effects of dietary 1,4-dihydropyridine on fatty liver of laying hens

浙江大学学报. 农业与生命科学版, 2003
Five hundred and fourty of laying hens at the age of 40 weeks were randomly allotted to 3 groups, each of which included 4 replicates of 45 hens. The groups were fed with a basal corn-soybean diet, supplemented with 0 (control),150 mg/kg, 300 mg/kg 1,4 ...
ZOU Xiao-ting, ZHU Jing-lan, XU Zi-rong
doaj   +1 more source

Bromination and Diazo-Coupling of Pyridinethiones; Microwave Assisted Synthesis of Isothiazolopyridine, Pyridothiazine and Pyridothiazepines

Molecules, 2012
Isothiazolopyridines, pyridothiazines and pyridothiazepines are important compounds that possess valuable biological activities. This paper reports on the synthesis of these compounds using both conventional chemical methods and modern microwave ...
Ayman M. S. Youssef, Mohamed E. Azab, Mohamed M. Youssef   +2 more
doaj   +1 more source

Chemoenzymatic Synthesis of Enantiopure 1,4‐Dihydropyridine Derivatives

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Sobolev, A., Franssen, M.C.R., Duburs, G., de Groot, Æ.   +3 more
openaire   +2 more sources

Establishing the Thermodynamic Cards of Dipine Models’ Oxidative Metabolism on 21 Potential Elementary Steps

Molecules
Dipines are a type of important antihypertensive drug as L-calcium channel blockers, whose core skeleton is the 1,4-dihydropyridine structure. Since the dihydropyridine ring is a key structural factor for biological activity, the thermodynamics of the ...
Guang-Bin Shen, Shun-Hang Gao, Yan-Wei Jia, Xiao-Qing Zhu, Bao-Chen Qian   +4 more
doaj   +1 more source

Crystal structure of ethyl 4-[4-(dimethylamino)phenyl]-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2018
In the title racemic compound, ethyl 4-(4-dimethylaminophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, the common structural features in this type of compound, such as the flat-boat conformation of the 1,4-dihydropyridine (1,4-
Scott A. Steiger, Chun Li, Nicholas R. Natale   +2 more
doaj   +1 more source

Synthesis and Aromatization of Hantzsch 1,4-Dihydropyridines under Microwave Irradiation. An Overview

Molecules, 2003
Domestic microwave ovens as well as laboratory reactors have been successfully employed to prepare dialkyl 1,4-dihydropyridine-3,5-dicarboxylates and to induce the synthesis of the corresponding aromatic derivatives.
Annie Mayence, Jean Jacques Vanden Eynde
doaj   +1 more source