Results 71 to 80 of about 121,691 (212)
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye +2 more
wiley +1 more source
1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone
In the title compound, C17H17Cl2NO2, the central 1,4-dihydropyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydropyridine ring at positions 3 and 5 have synperiplanar (cis) or antiperiplanar (trans) conformations ...
J. Kalyana Sundar +5 more
doaj +1 more source
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 1,4-DIHYDROPYRIDINE DERIVATIVE
A series of substituted 1,4-dihydopyridine derivatives (SC1-SC10) was synthesized via condensation of acetoacetanilide /4-chloro acetoacetanilide and substituted benzaldehyde in methanol with excess amount of ammonia.
Soni, Love Kumar +2 more
core +1 more source
One-Pot Synthesis of 1,4-Dihydropyridine Derivatives and their X-Ray Crystal Structures: Role of Fluorine in Weak Interactions [PDF]
1,4-dihydropyridines, namely diethyl 4-(4-fluorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (1a), diethyl 2,6-dimethyl-4-(3,4,5-trimethoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate(1b), and diethyl 4-(3,4-dimethoxyphenyl)-2,6-dihydroxy ...
Shashi, R., Prasad, N.L., Begum, N.S.
core +1 more source
Bis‐Furans: A Sustainable Source of Diverse Molecular Architectures
A concise synthetic route to diverse acyclic and heterocyclic compounds has been developed by combining hetero‐Diels–Alder reactions, DBU‐promoted ring openings, and Lewis base‐catalyzed annulations. Nitrosoalkenes reacted with furan derivatives to form 4a,7a‐dihydro‐4H‐furo[2,3‐e][1,2]oxazines, which underwent DBU‐promoted rearrangements to 6H‐1,2 ...
Ana L. Cardoso +2 more
wiley +1 more source
Diisobutyl 4-(3-ethoxy-4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
The asymmetric unit of the title compound, C25H35NO6, contains two independent molecules. In each molecule, the 1,4-dihydropyridine ring adopts a flattened boat conformation. The dihedral angles between the 1,4-dihydropyridine and benzene rings are 87.55&
Hoong-Kun Fun +4 more
doaj +1 more source
Radical Retrosynthesis of Natural Products Enabled by Iron‐Based Reductive Olefin Coupling
This review highlights iron‐catalyzed reductive olefin coupling (ROC)—a strategy for C─C bond formation driven by metal‐hydride hydrogen atom transfer (MHAT)—as a key tool in natural products synthesis. This review surveys dozens of total syntheses employing ROC‐based strategies, highlighting its power to forge strained rings, quaternary centers, and ...
Griffin L. Barnes +2 more
wiley +1 more source
Electrogeneration of nitranion species from nitrofuryl substituted 1,4-dihydropyridine derivatives [PDF]
We have synthesized and studied the electroreduction of 1,4-dihydropyridine derivatives with a nitrofuryl substituent at 4-position. The one-electron reduction of these compounds in non-aqueous medium generates the corresponding nitro radical anion.
Squella Serrano, Juan +2 more
core
Tandem mechanochemical‐sonochemical for the strategic synthesis for 2,4,6‐trisubstituted derivatives of perfluoropyridine as bio‐based prepolymer materials. ABSTRACT Substitution of perfluoropyridine (PFP) in the 4‐position through an SNAr reaction is facile through mechanochemical methods, with yields in excess of 99% and short reaction times on a ...
Jason Pulfer +5 more
wiley +1 more source
Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos +3 more
wiley +1 more source

