Results 91 to 100 of about 121,691 (212)
MoleculesDipines are a type of important antihypertensive drug as L-calcium channel blockers, whose core skeleton is the 1,4-dihydropyridine structure. Since the dihydropyridine ring is a key structural factor for biological activity, the thermodynamics of the ...
Guang-Bin Shen +4 more
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Tissue-specific expression of calcium channels [PDF]
, 1993 The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Flockerzi, Veit +3 more
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Acta Crystallographica Section E: Crystallographic Communications, 2018 In the title racemic compound, ethyl 4-(4-dimethylaminophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, the common structural features in this type of compound, such as the flat-boat conformation of the 1,4-dihydropyridine (1,4-
Scott A. Steiger +2 more
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Molecules, 2003 Domestic microwave ovens as well as laboratory reactors have been successfully employed to prepare dialkyl 1,4-dihydropyridine-3,5-dicarboxylates and to induce the synthesis of the corresponding aromatic derivatives.
Annie Mayence, Jean Jacques Vanden Eynde
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Proaromatic electron donors based on 1,4 dihydropyridine
, 2018 Byla provedena literární rešerše zabývající se problematikou proaromatických elektron donorů na bázi 1,4-dihydropyridinu. Nejprve byly popsány obecné vlastnosti push-pull sytémů.
Holíková, Kristýna
core
Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists. [PDF]
Int J Mol Sci, 2023 Pérez-Gordillo FL +9 more
europepmc +1 more source
Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
Acta Crystallographica Section E, 2011 The title compound, C17H16N2O6, is a decomposition product of the hypertension drug nifedipine [systematic name: dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate].
Juanjuan Zheng +4 more
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Chemoenzymatic synthesis of enantiopure 1,4-dihydropyridine derivatives
, 2003 Chirality is important for the activity of many biologically active compounds, since differences in biological properties of stereoisomers occur frequently.
Sobolev, A.
core
Synthesis and crystal structure of a novel substituted 1,4-dihydropyridine [PDF]
, 2007 The title compound, C15H16N2O3, was synthesized, characterized spectroscopically, and finally confirmed by X-ray diffraction studies. The compound crystallizes in the monoclinic space group P21/n with cell parameters a = 10.314(9) Å, b = 17.976(15) Å, c =
Naveen, S. +7 more
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Revista CENIC Ciencias Químicas, 2000 1,4-dihydropyridine (1,4-DHPs) are well known compounds as a consequence of their pharmacological profile as calcium channel modulator. The chemical modifications carried out on the DHP ring such as the presence of different substituents have allowed ...
Julio Duque +6 more
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