Results 91 to 100 of about 8,139 (202)
Photodecomposition of a New 1,4-Dihydropyridine: Furnidipine
Journal of Pharmaceutical Sciences, 1994 The photodecomposition of new 1,4-dihydropyridine, furnidipine (CRE-319); [2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-tetrahydrofurfuryl 5-methyl diester) was studied by voltammetric, UV-vis spectrophotometric, and HPLC technique with three different light conditions (artificial daylight, UV light, and room daylight ...
Núñez Vergara, Luis +2 more
openaire +3 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C23H24BrNO5, the central 1,4-dihydropyridine ring of the 1,2,3,4,5,6,7,8,9,10-decahydroacridine ring system adopts a half-chair conformation. The two cyclohexene rings fused to the central ring both have a twisted-boat conformation.
Shaaban K. Mohamed +5 more
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Molbank, 2011 One-pot two-step Hantzsch synthesis of 4-(3,5-dibromo-4-hydroxyphenyl)-3- butoxycarbonyl-5-ethoxycarbonyl-2-methyl-6-phenyl-1,4-dihydropyridine under solvent- and catalyst-free conditions promoted with microwave irradiation is presented.
Zhen Wang, Qingjian Liu
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CXCL12-induced neurotoxicity critically depends on NMDA receptor-gated and L-type Ca2+ channels upstream of p38 MAPK. [PDF]
, 2016 BackgroundThe chemokine receptor CXCR4 (CD184) and its natural ligand CXCL12 contribute to many physiological processes, including decisions about cell death and survival in the central nervous system.
Kaul, Marcus +5 more
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Synthesis of 1,4-Dihydropyridine Derivatives Under Aqueous Media
E-Journal of Chemistry, 2010 An environmental friendly synthesis of 1,4-dihydropyridine derivatives was developed by the one-pot reaction of aldehydes, ethyl acetoacetate and ammonia in water under refluxing conditions.
Adeleh Moshtaghi Zonouz +1 more
doaj +1 more source
Effects of dietary 1,4-dihydropyridine on fatty liver of laying hens
浙江大学学报. 农业与生命科学版, 2003 Five hundred and fourty of laying hens at the age of 40 weeks were randomly allotted to 3 groups, each of which included 4 replicates of 45 hens. The groups were fed with a basal corn-soybean diet, supplemented with 0 (control),150 mg/kg, 300 mg/kg 1,4 ...
ZOU Xiao-ting, ZHU Jing-lan, XU Zi-rong
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Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame. [PDF]
, 2016 The endoplasmic reticulum (ER)-anchored hepatic cytochromes P450 (P450s) are enzymes that metabolize endo- and xenobiotics i.e. drugs, carcinogens, toxins, natural and chemical products.
Correia, Maria Almira +4 more
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Molecules, 2012 Isothiazolopyridines, pyridothiazines and pyridothiazepines are important compounds that possess valuable biological activities. This paper reports on the synthesis of these compounds using both conventional chemical methods and modern microwave ...
Ayman M. S. Youssef +2 more
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Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis [PDF]
, 2016 Background: Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder that is typically fatal within 3–5 years of diagnosis. While motoneuron death is the defining characteristic of ALS, the events that underlie its pathology are
Bannister, Roger A. +6 more
core +2 more sources
MoleculesDipines are a type of important antihypertensive drug as L-calcium channel blockers, whose core skeleton is the 1,4-dihydropyridine structure. Since the dihydropyridine ring is a key structural factor for biological activity, the thermodynamics of the ...
Guang-Bin Shen +4 more
doaj +1 more source