Results 101 to 110 of about 8,139 (202)

Vasorelaxant Effect of a Newly Synthesized Dihydropyridine Ethyl Ester (DHPEE) on Rat Thoracic Aorta: Dual Mechanism of Action [PDF]

, 2011
Introduction: DHPEE is a newly synthesized compound by merging the key structural elements in an angiotensin receptor blocker (Telmisartan) with key structural elements in 1,4- dihydropyridine calcium channel blocker (Nifedipine).
Afsaneh Gharehbagheri, Farzaneh Ebrahimi, Hossein Babaei, Javid Shahbazi Mojarrad, Yadollah Azarmi   +4 more
core  

Antileishmanial and Antitoxoplasmal Activities of 1,4-dihydropyridines

ACS Omega
Abstract: We have synthesized 24 1,4-dihydropyridine compounds (1,4-DHPs) with different substituents at the aromatic ring by microwave-assisted one-pot Hantzsch multicomponent reac-tion and evaluated their in vitro activities against Toxoplasma gondii and Leishmania major.
Thaís Oliveira, Yan Robles, Ibrahim Al Nasr, Waleed Koko, Tariq Khan, Ismail Daoud, Seyfeddine Rahali, Noureddine Amdouni, Ridha Ben Said, Antônio Crotti   +9 more
openaire   +2 more sources

Crystal structure of ethyl 4-[4-(dimethylamino)phenyl]-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2018
In the title racemic compound, ethyl 4-(4-dimethylaminophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, the common structural features in this type of compound, such as the flat-boat conformation of the 1,4-dihydropyridine (1,4-
Scott A. Steiger, Chun Li, Nicholas R. Natale   +2 more
doaj   +1 more source

Дилудин и цереброкраст как биопротекторы в модельных тест-системах in vivo [PDF]

, 2009
Изучено влияние двух производных 1,4-дигидропиридина — дилудина и цереброкраста — на развитие дрозофилы и мутабильность половых клеток. Выявлен диапазон доз, в котором препараты проявляют биостимулирующие эффекты, повышая на 50–80 % выживаемость особей ...
Даливеля, Ольга Вячеславовна
core  

Synthesis and Aromatization of Hantzsch 1,4-Dihydropyridines under Microwave Irradiation. An Overview

Molecules, 2003
Domestic microwave ovens as well as laboratory reactors have been successfully employed to prepare dialkyl 1,4-dihydropyridine-3,5-dicarboxylates and to induce the synthesis of the corresponding aromatic derivatives.
Annie Mayence, Jean Jacques Vanden Eynde
doaj   +1 more source

Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists. [PDF]

Int J Mol Sci, 2023
Pérez-Gordillo FL, Serrano-Morillas N, Acosta-García LM, Aranda MT, Passeri D, Pellicciari R, Pérez de Vega MJ, González-Muñiz R, Alvarez de la Rosa D, Martín-Martínez M.   +9 more
europepmc   +1 more source

Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate

Acta Crystallographica Section E, 2011
The title compound, C17H16N2O6, is a decomposition product of the hypertension drug nifedipine [systematic name: dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate].
Juanjuan Zheng, Xueyuan Wang, Dongying Pang, Yan Sun, Wei Su   +4 more
doaj   +1 more source

Conformational study of 3-acety 1-2, 7, 7-trimethyl-4-phenyl- 1,4,S,6, 7,8-hexahydro-5-quinolone starting from the crystallo­graphics datas

Revista CENIC Ciencias Químicas, 2000
1,4-dihydropyridine (1,4-DHPs) are well known compounds as a consequence of their pharmacological profile as calcium channel modulator. The chemical modifications carried out on the DHP ring such as the presence of different substituents have allowed ...
Julio Duque, Ramón Pomés, Margarita Suárez, Y. Verdecía, E. Ochoa, G. Puntee, G. Echevarría   +6 more
doaj  

1,4-Dihydropyridine: synthetic advances, medicinal and insecticidal properties. [PDF]

RSC Adv, 2022
A P, Makam P.
europepmc   +1 more source

Retraction: Synthesis of efficient cobalt-metal organic framework as reusable nanocatalyst in the synthesis of new 1,4-dihydropyridine derivatives with antioxidant activity. [PDF]

Front Chem, 2023
Frontiers Editorial Office.
europepmc   +1 more source