Results 1 to 10 of about 178,151 (198)

Development of Self-Assembling bis-1,4-Dihydropyridines: Detailed Studies of Bromination of Four Methyl Groups and Bromine Nucleophilic Substitution

Molecules, 2023
One of the most important steps in the synthesis of 1,4-dihydropyridine (1,4-DHP) amphiphiles is the bromination of methyl groups in positions 2 and 6 of the entire ring.
Martins Kaukulis, Martins Rucins, Davis Lacis, Aiva Plotniece, Arkadij Sobolev   +4 more
doaj   +1 more source

Cosmological Evolution of Supergiant Star-Forming Clouds [PDF]

, 2001
In an exploration of the birthplaces of globular clusters, we present a careful examination of the formation of self-gravitating gas clouds within assembling dark matter haloes in a hierarchical cosmological model.
Black J. H., Bower R. G., Efstathiou G., Fall S. M., Gingold R. A., Lacey C., Melinda L. Weil, Oort J. H., Ralph E. Pudritz, Steinmetz M., Weil M. L., White S. D. M   +11 more
core   +2 more sources

1,1′-{[3,5-Bis(dodecyloxycarbonyl)-4-(naphthalen-2-yl)-1,4-dihydropyridine-2,6-diyl]bis(methylene)}bis{4-[(E)-2-(naphthalen-2-yl)vinyl]pyridin-1-ium}dibromide

Molbank, 2022
Synthesis of a double-charged cationic amphiphilic 1,4-dihydropyridine derivative with dodecyl ester groups at positions 3 and 5 of the 1,4-DHP ring was performed starting from Hantzsch type cyclization of dodecyl acetoacetate, 2-naphthaldehyde and ...
Martins Rucins, Martins Kaukulis, Aiva Plotniece, Karlis Pajuste, Nadiia Pikun, Arkadij Sobolev   +5 more
doaj   +1 more source

Self-Assembly of Patchy Particles into Polymer Chains: A Parameter-Free Comparison between Wertheim Theory and Monte Carlo Simulation

, 2007
We numerically study a simple fluid composed of particles having a hard-core repulsion, complemented by two short-ranged attractive (sticky) spots at the particle poles, which provides a simple model for equilibrium polymerization of linear chains.
Emanuela Bianchi, Flory P. J., Francesco Sciortino, Hausen J. P., Hill T. L., Jack F. Douglas, Jones R., Piero Tartaglia, Smith B.   +8 more
core   +1 more source

HydrogelFinder: A Foundation Model for Efficient Self‐Assembling Peptide Discovery Guided by Non‐Peptidal Small Molecules

Advanced Science
Self‐assembling peptides have numerous applications in medicine, food chemistry, and nanotechnology. However, their discovery has traditionally been serendipitous rather than driven by rational design.
Xuanbai Ren, Jiaying Wei, Xiaoli Luo, Yuansheng Liu, Kenli Li, Qiang Zhang, Xin Gao, Sizhe Yan, Xia Wu, Xingyue Jiang, Mingquan Liu, Dongsheng Cao, Leyi Wei, Xiangxiang Zeng, Junfeng Shi   +14 more
doaj   +1 more source

Novel Benzothiazole Boc-Phe-Phe-Bz Derivative Dipeptide Forming Fluorescent and Nonlinear Optical Self-Assembled Structures

Molecules
This work explores the self-assembly and optical properties of a novel chiral, aromatic-rich Boc-Phe-Phe dipeptide derivative functionalized with a benzothiazole bicyclic ring that forms supramolecular structures.
Rosa M. F. Baptista, Daniela Santos, N. F. Cunha, Maria Cidália R. Castro, Pedro V. Rodrigues, Ana V. Machado, Michael S. Belsley, Etelvina de Matos Gomes   +7 more
doaj   +1 more source

Synthesis and Evaluation of Self-Assembling Properties of 3-(3,5-Difluoro-3,5-bis((alkoxy)carbonyl)-2,6-dioxoheptan-4-yl)-1-methylpyridin-1-ium Iodides

Molbank, 2022
A synthesis of 3-(3,5-difluoro-3,5-bis((alkoxy)carbonyl)-2,6-dioxoheptan-4-yl)-1-methylpyridin-1-ium iodides with ethyl or nonyl ester groups at positions 3 and 5 was performed. Treatment of the corresponding 2’,6’-dimethyl-1’,4’-dihydro-[3,4’-bipyridine]
Nadiia Pikun, Davis Lacis, Arkadij Sobolev, Martins Rucins, Mara Plotniece, Karlis Pajuste, Aiva Plotniece   +6 more
doaj   +1 more source

Using the uncertainty principle to design simple interactions for targeted self-assembly [PDF]

, 2012
We present a method that systematically simplifies isotropic interactions designed for targeted self-assembly. The uncertainty principle is used to show that an optimal simplification is achieved by a combination of heat kernel smoothing and Gaussian ...
Badii R., E. Edlund, M. Nilsson Jacobi, O. Lindgren   +3 more
core   +2 more sources

Self-assembly properties of a model RING domain [PDF]

Proceedings of the National Academy of Sciences, 2002
RING domains act in a variety of essential cellular processes but have no general function ascribed to them. Here, we observe that purified arenaviral protein Z, constituted almost entirely by its RING domain, self-assembles in vitro into spherical structures that resemble functional bodies formed by Z in infected ...
Alex, Kentsis, Ronald E, Gordon, Katherine L B, Borden   +2 more
openaire   +2 more sources

Mechanics and kinetics of dynamic instability

eLife, 2020
During dynamic instability, self-assembling microtubules (MTs) stochastically alternate between phases of growth and shrinkage. This process is driven by the presence of two distinct states of MT subunits, GTP- and GDP-bound tubulin dimers, that have ...
Thomas CT Michaels, Shuo Feng, Haiyi Liang, L Mahadevan   +3 more
doaj   +1 more source