Self-assembling peptides as immunomodulatory biomaterials [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 Self-assembling peptides are a type of biomaterial rapidly emerging in the fields of biomedicine and material sciences due to their promise in biocompatibility and effectiveness at controlled release.
Andrea Hernandez +2 more
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Deep Learning Empowers the Discovery of Self‐Assembling Peptides with Over 10 Trillion Sequences [PDF]
Advanced Science, 2023 Self‐assembling of peptides is essential for a variety of biological and medical applications. However, it is challenging to investigate the self‐assembling properties of peptides within the complete sequence space due to the enormous sequence quantities.
Jiaqi Wang +6 more
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Self-assembling peptides-based nano-cargos for targeted chemotherapy and immunotherapy of tumors: recent developments, challenges, and future perspectives [PDF]
Drug Delivery, 2022 Self-assembling peptides (SAPs) have enormous potential in medical and biological applications, particularly noninvasive tumor therapy. SAPs self-assembly is governed by multiple non-covalent interactions and results in the formation of a variety of ...
Xue-Jun Wang +3 more
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 Ion-complementary self-assembling peptides have potential in delivering hydrophobic drugs. This study involved two self-assembling peptides, RADA16-I and RVDV16-I, of which RVDV16-I was a novel self-assembling peptide with different hydrophobic side ...
Weipeng Wei +8 more
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Supramolecular Nanomedicines of In-Situ Self-Assembling Peptides [PDF]
Frontiers in Chemistry, 2022 Nanomedicines provide distinct clinical advantages over traditional monomolecular therapeutic and diagnostic agents. Supramolecular nanomedicines made from in-situ self-assembling peptides have emerged as a promising strategy in designing and fabricating
Ying Zhang, Yingying Yu, Jie Gao
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A novel protein purification scheme based on salt inducible self-assembling peptides [PDF]
Microbial Cell Factories, 2023 Background Protein purification remains a critical need for biosciences and biotechnology. It frequently requires multiple rounds of chromatographic steps that are expensive and time-consuming. Our lab previously reported a cleavable self-aggregating tag
Guang Zeng +5 more
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De Novo Self-Assembling Peptides Mediate the Conversion of Temozolomide and Delivery of a Model Drug into Glioblastoma Multiforme Cells [PDF]
Biomedicines, 2022 Glioblastoma multiforme (GBM) is the most aggressive central nervous system tumor, and standard treatment, including surgical resection, radiation, and chemotherapy, has not significantly improved patient outcomes over the last 20 years.
Megan Pitz +5 more
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Encapsulation of zingerone by self-assembling peptides derived from fish viscera: Characterization, interaction and effects on colon epithelial cells [PDF]
Food Chemistry: XThe purpose of the present work was to encapsulate zingerone (a bioactive compound from ginger) by self-assembling peptides derived from fish viscera. The encapsulation conditions were investigated and the structure of fish peptides-zingerone complex was
Sirong Huang +6 more
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Nontoxic mRNA vehicles based on electrically neutral self-assembling peptides [PDF]
Nature CommunicationsThe cationic molecules and low-molecular-weight amphiphiles commonly used in nonviral gene delivery vehicles often induce adverse nonspecific effects, notably cytotoxicity and detergent-like unfavourable membrane activity.
Zhihao Zhang +5 more
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Enhancing the Biological Functionality of Hydrogels Using Self-Assembling Peptides [PDF]
BiomimeticsHydrogels are ECM-mimicking three-dimensional (3D) networks that are widely used in biomedical applications; however, conventional natural and synthetic polymer-based hydrogels present limitations such as poor mechanical strength, limited bioactivity ...
Woo Hyun Kwon +7 more
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