Rapid discovery of self-assembling peptides with one-bead one-compound peptide library [PDF]
Nature Communications, 2021 Self-assembling peptides have a range of potential applications but developing self-assembling sequences can be challenging. Here, the authors report on a one-bead one-compound combinatorial library where fluorescence is used to detect the potential for ...
Pei-Pei Yang +13 more
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Self-assembling peptide scaffolds in the clinic [PDF]
npj Regenerative Medicine, 2021 Well-defined scaffold hydrogels made of self-assembling peptides have found their way into clinical products. By examining the properties and applications of two self-assembling peptides—EAK16 and RADA16—we highlight the potential for translating ...
Fabrizio Gelain +3 more
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Self-Assembling Peptides and Carbon Nanomaterials Join Forces for Innovative Biomedical Applications [PDF]
Molecules, 2021 Self-assembling peptides and carbon nanomaterials have attracted great interest for their respective potential to bring innovation in the biomedical field.
Petr Rozhin +2 more
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Self-Assembling Peptides for Vaccine Adjuvant Discovery
ImmunoVaccination is credited as a significant medical achievement contributing to the decline in morbidity and mortality of infectious diseases. Traditional vaccines composed of inactivated and live-attenuated whole pathogens confer the induction of potent ...
Jingyi Fan +2 more
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Discovery and design of self-assembling peptides [PDF]
Interface Focus, 2017 Abstract Peptides are ubiquitous in nature and useful in many fields, from agriculture as pesticides, in medicine as antibacterial and antifungal drugs founded in the innate immune systems, to medicinal chemistry as hormones. However, the concept of peptides as materials was not recognized until 1990 when a self-assembling peptide as ...
Shuguang Zhang
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Amphiphilic peptides as novel nanomaterials: design, self-assembly and application
International Journal of Nanomedicine, 2018 Feng Qiu,1,2 Yongzhu Chen,2,3 Chengkang Tang,2,4 Xiaojun Zhao2 1Laboratory of Anaesthesia and Critical Care Medicine, Translational Neuroscience Centre, West China Hospital, Sichuan University, Chengdu 610041, China; 2Institute for Nanobiomedical ...
Qiu F, Chen Y, Tang C, Zhao X
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Efficacy of RADA16-Based Self-Assembling Peptides on Wound Healing: A Meta-Analysis of Preclinical Animal Studies [PDF]
PharmaceuticalsObjectives: This analysis aims to provide evidence supporting the feasibility of clinical application of self-assembling peptides for skin wound healing.
Jiaju Lu +3 more
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Self-assembling peptides as bioactive coatings
Biomaterials ScienceSelf-assembling peptides (SAPs), featuring programmable sequences, supramolecular assembly, modular functional integration and environmental responsiveness, offer a versatile platform to fabricate tunable, designable bioactive coatings.
Ruonan Zhang +3 more
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A New Hope: Self-Assembling Peptides with Antimicrobial Activity
Pharmaceutics, 2019 Peptide drugs hold great promise for the treatment of infectious diseases thanks to their novel mechanisms of action, low toxicity, high specificity, and ease of synthesis and modification.
Lucia Lombardi +3 more
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Recent advances in self-assembling peptide matrices as functional coatings for implantable devices
Frontiers in Chemistry, 2022 Nature has evolved numerous supramolecular machineries for modulating various cellular functions. Inspired by the assembly of these sophisticated structures in nature, the controlled assembly of synthetic peptides emerges as a promising approach to ...
Yuan Tian, Lei Lu
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