Results 41 to 50 of about 116,777 (208)

Selective Mono Bromination of 1,4-Dihydropyridines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1997
2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °C. The same reagent in dichloromethane at 0 °C produce the 2,6-
Yousef Rastgar Mirzaei, Adeleh Moshtaghi Zenouz   +1 more
doaj  

SYNTHESIS OF SOME 2,7-DIAZABICYCLO {4.l.0} HEPT-3-ENE DERIVATIVES WITH ANALGESIC AND ANTICOCCIDIAL ACTIVITY [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 1986
The 1,3-dipolar cycloaddition reaction of arylsulphonyl azides to 1,3-disubstituted-1,4-dihydropyridines afforded 2,7-diazabieyclo {4.1.0} hept-3-ene derivatives (III).These compounds exhibited more significant analgesic and anticoccidial activities than
A. El-Badr, R. Abdel-Aal, H. Hemaiat-Allah, H. Hassan, A. Abdel-Alim, H. Farag   +5 more
doaj   +1 more source

Cobalt(II)-Catalyzed C–H Alkylation of N‑Heterocycles with 1,4-Dihydropyridines

, 2022
The rapid incorporation of alkyl and acyl groups into C–H bonds of N-heterocycles is in demand for the development of lead candidates in drug discovery.
Prithwish Ghosh (7122755), In Su Kim (1433776), Jung Su Park (1449832), Neeraj Kumar Mishra (1565998), Youjung Byun (10750326), Na Yeon Kwon (6102161)   +5 more
core   +1 more source

Enaminones in a multicomponent synthesis of 4-aryldihydropyridines for potential applications in photoinduced intramolecular electron-transfer systems

Beilstein Journal of Organic Chemistry, 2012
An efficient three component reaction with enaminones, primary amines and aldehydes resulted in easy access to 1,4-dihydropyridines with different substituents at the 1-, 3-, 4- and 5-positions.
Nouria A. Al-Awadi, Maher R. Ibrahim, Mohamed H. Elnagdi, Elizabeth John, Yehia A. Ibrahim   +4 more
doaj   +1 more source

One-pot multicomponent green Hantzsch synthesis of 1,2-dihydropyridine derivatives with antiproliferative activity

Beilstein Journal of Organic Chemistry, 2020
A rapid route for obtaining unsymmetrical 1,2-dihydropyridines (1,2-DHPs) as opposed to 1,4-dihydropyridines (1,4-DHPs) has been achieved via a one-pot multicomponent Hantzsch reaction.
Giovanna Bosica, Kaylie Demanuele, José M. Padrón, Adrián Puerta   +3 more
doaj   +1 more source

An Efficient One-Pot Three-Component Synthesis of Fused 1,4-Dihydropyridines Using HY-Zeolit

Molecules, 2009
A facile and convenient protocol was developed for the fast (2.5-3.5 h) and high yielding (70-90 %) synthesis of fused 1,4-dihydropyridines from dimedone in the presence of HY-zeolite as an efficient recyclable heterogeneous catalyst.
Khalil Tabatabaeian, Mohammad Nikpassand, Manouchehr Mamaghani   +2 more
doaj   +3 more sources

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates

Molecules, 2015
The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions.
Brigita Vigante, Martins Rucins, Aiva Plotniece, Karlis Pajuste, Iveta Luntena, Brigita Cekavicus, Egils Bisenieks, Rufus Smits, Gunars Duburs, Arkadij Sobolev   +9 more
doaj   +1 more source

N,N'-Ethylene-bis(benzoylacetoniminato) Copper (II), Cu(C22H22N2O2), a New Reagent for Aromatization of Hantzsch 1,4-Dihydropyridines

Molecules, 2007
A variety of Hantzsch 1,4-dihydropyridines were oxidized to their corresponding pyridines in high yields in the presence of Cu(C22H22N2O2) in refluxing acetic acid.
Majid M Heravi, Saeed Dehghanpour, Fatemeh Derikvand   +2 more
doaj   +1 more source

Hantzsch Reaction Starting Directly from Alcohols through a Tandem Oxidation Process

Journal of Chemistry, 2017
A Brønsted acidic ionic liquid, 3-(N,N-dimethyldodecylammonium) propanesulfonic acid hydrogen sulphate ([DDPA][HSO4]), has been successfully applied to catalyze sequential oxidation of aromatic alcohols with NaNO3 followed by their condensation with ...
Xiaobing Liu, Bin Liu
doaj   +1 more source

Hantzsch-Type Dihydropyridines and Biginelli-Type Tetra-hydropyrimidines: A Review of their Chemotherapeutic Activities

Journal of Pharmacy & Pharmaceutical Sciences, 2015
Years after the first report on 1,4-dihydropyridines (1,4-DHPs) and 1,2,3,4-tetrahydropyrimidines (1,2,3,4-THPMs) appeared, they  are revisited as plausible therapeutic agents.
Saghi Sepehri, Horacio Perez Sanchez, Afshin Fassihi   +2 more
doaj   +1 more source