Results 31 to 40 of about 362,486 (169)

Oxidative aromatization of Hantzsch 1,4-dihydropyridines by sodium chlorite

, 2010
Hantzsch 1,4-dihydropyridines were converted to the corresponding pyridines efficiently by sodium chlorite under mild conditions in excellent yields. (C) 2010 Elsevier Ltd.
Lin, Wenbin, Liao, Xiali, Lu, Jun, Wang, C, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China, Wang, Chun, Chun Wang, Xiali Liao, Wenbin Lin, Jun Lu   +8 more
core   +1 more source

Hantzsch Reaction Starting Directly from Alcohols through a Tandem Oxidation Process

Journal of Chemistry, 2017
A Brønsted acidic ionic liquid, 3-(N,N-dimethyldodecylammonium) propanesulfonic acid hydrogen sulphate ([DDPA][HSO4]), has been successfully applied to catalyze sequential oxidation of aromatic alcohols with NaNO3 followed by their condensation with ...
Xiaobing Liu, Bin Liu
doaj   +1 more source

An efficient Hantzsch synthesis of 1,4-dihydropyridines using p-toluenesulfonic acid under solvent-free condition [PDF]

Maejo International Journal of Science and Technology, 2014
An efficient Hantzsch synthesis of various substituted 1,4-dihydropyridines from an aldehyde, a β-dicarbonyl compound and ammonium acetate using p-toluenesulfonic acid in a solvent-free condition in the absence of any other co ...
Masoud Nasr-Esfahani , Morteza Montazerozohori , Razieh Raeatikia   +2 more
doaj   +1 more source

Hantzsch-Type Dihydropyridines and Biginelli-Type Tetra-hydropyrimidines: A Review of their Chemotherapeutic Activities

Journal of Pharmacy & Pharmaceutical Sciences, 2015
Years after the first report on 1,4-dihydropyridines (1,4-DHPs) and 1,2,3,4-tetrahydropyrimidines (1,2,3,4-THPMs) appeared, they  are revisited as plausible therapeutic agents.
Saghi Sepehri, Horacio Perez Sanchez, Afshin Fassihi   +2 more
doaj   +1 more source

Dihydropyridines Potentiate ATP-Induced Currents Mediated by the Full-Length Human P2X5 Receptor

Molecules, 2022
The P2X5 receptor, an ATP-gated cation channel, is believed to be involved in tumor development, inflammatory bone loss and inflammasome activation after bacterial infection. Therefore, it is a worthwhile pharmacological target to treat the corresponding
Ida C. Schiller, Kenneth A. Jacobson, Zhiwei Wen, Aparna Malisetty, Günther Schmalzing, Fritz Markwardt   +5 more
doaj   +1 more source

Study of anti-inflammatory and antinociceptive properties of new derivatives of condensed 3-aminothieno[2,3-b]pyridines and 1,4-dihydropyridines

Acta Biomedica Scientifica, 2023
Background. α-сyanothioacetamide derivatives are promising targets for the search for effective and safe antinociceptive agents with antipyretic and antiexudative activity. The aim. To conduct in vivo experimental study of anti-inflammatory and analgesic
I. V. Bibik, E. Yu. Bibik, A. A. Pankov, K. A. Frolov, V. V. Dotsenko, S. G. Krivokolysko   +5 more
doaj   +1 more source

Synthesis of 2-Mono and 2,6-Disubstituted Methyl-1,4-Dihydropyridines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1997
The 2-mono and 2,6-disubstituted methyl-1,4-dihydropyridines were synthesized by reaction of morpholine, thiophenol, 8-hydroxyquinoline, 2-naphthol and 2-mercopto-1-methyl imidazole with the 2-mono bromo and 2,6-dibromo-1,4-dihidropyridines.
Yousef Rastgar Mirzaei, Karim Akbari Dilmaghani   +1 more
doaj  

Catalytic Asymmetric Synthesis of Both Enantiomers of 4‑Substituted 1,4-Dihydropyridines with the Use of Bifunctional Thiourea-Ammonium Salts Bearing Different Counterions

Molecules, 2010
Organoammonium salts composed of a Brønsted acid and an anilinothiourea promoted the Michael addition of β-keto esters and α,β-unsaturated aldehydes in the presence of primary amines to give functionalized 1,4-dihydropyridines enantioselectively.
Kohzo Yoshida, Tsubasa Inokuma, Kiyosei Takasu, Yoshiji Takemoto   +3 more
doaj   +1 more source

Gold‐Catalyzed Cyclization of Indole‐Tethered Alkynes Enabling Synthesis of Exocyclic Alkenyl Tetrahydrocarbazoles

European Journal of Organic Chemistry, EarlyView.
An efficient gold‐catalyzed intramolecular cyclization of indole‐tethered alkynes using AgNTf2 as an additive has been developed, which provides bioactive exocyclic alkenyl tetrahydrocarbazoles with up to 85% yield. Control experiments and DFT studies indicate that the reaction proceeds via a 6‐exo‐dig cyclization pathway, with gold acetylide complexes
Haibo Mei, Jingrui He, Chengting Wang, Jorge Escorihuela, Jianlin Han   +4 more
wiley   +1 more source

Face-Selective Addition to a Cation−π Complex of a Pyridinium Salt:  Synthesis of Chiral 1,4-Dihydropyridines

, 2016
Selective shielding of one side of the pyridinium face by way of intramolecular cation−π complex formation enabled nucleophiles to attack only from the non-shielded side, and consequently, chiral 1,4-dihydropyridines were produced stereoselectively with ...
Shinji Yamada (1488268), Chisako Morita (2988183)   +1 more
core   +1 more source