Carbon Resources Conversion, 2019 A novel Acetazolamide condensed 1, 4-dihydropyridines was set up by treating of N-(5-acetamido-1, 3, 4-thiadiazol-2-ylsulfonyl)-3-oxobutanamide with an aryl aldehyde and 25–30% alkali with sight amount of barium nitrate as a catalyst. Confirmation of the
Mudduluru Niranjan Babu +5 more
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Results in Chemistry, 2023 Derivatives of dihydropyridines are promising agents for research, as they have high biological activity. Their low toxicity and polytargeted properties make it possible to create new derivatives and identify new biological activity. As part of this work,
Arkadiy Bryzgalov +3 more
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A copper-benzotriazole based coordination polymer catalyzes the efficient one-pot synthesis of (N'-substituted)-hydrazo-4-aryl-1,4-dihydropyridines from azines [PDF]
, 2017 A series of new (N’-substituted)-hydrazo-4-aryl-1,4 dihydropyridines were successfully synthesized via a facile one pot catalytic pathway utilizing azines and propiolate esters as starting materials and 1D Cu benzotriazoles based coordination polymer as ...
Batten +39 more
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Synthesis and reactivity of N-alkyl-2-oxoalkanesulfonamides [PDF]
, 1998 A series of N-alkyl-2-oxoalkanesulfonamides have been synthesized by reacting silyl enol ethers with N-alkyl-sulfamoyl chlorides. Their reactivity towards electrophiles was investigated in order to explore the regio-and stereoselectivity of the process ...
Alajarín Ferrández, Ramón +3 more
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A Microwave-Assisted Bismuth Nitrate-Catalyzed Unique Route Toward 1,4-Dihydropyridines
Molecules, 2012 The classical Hantzsch reaction is one of the simplest and most economical methods for the synthesis of biologically important and pharmacologically useful 1,4-dihydropyridine derivatives.
Bimal K. Banik +2 more
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Remote functionalisation via sodium alkylamidozincate intermediates : access to unusual fluorenone and pyridyl ketone reactivity patterns [PDF]
, 2011 Treating fluorenone or 2-benzoylpyridine with the sodium zincate [(TMEDA)center dot Na(mu-Bu-t)(mu-TMP)Zn(Bu-t)] in hexane solution, gives efficient Bu-t addition across the respective organic substrate in a highly unusual 1,6-fashion, producing isolable
Crawford, James J. +5 more
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Rearrangement of o-Nitrobenzaldehyde in the Hantzsch Reaction
Molecules, 2001 The reaction of 5-hydroxy-2-nitrobenzaldehyde with ethyl acetoacetate in ammonia gave the two expected isomeric 1,4- and 1,2-dihydropyridines resulting from the normal Hantzsch reaction.
R. MartÃÂnez +7 more
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Ultrasound Mediated, Green Innovation for the Synthesis of Polysubstituted 1,4-Dihydropyridines [PDF]
, 2016 An elegant, atom efficient protocol via a one-pot four-component cyclocondensation reaction of aromatic aldehydes, malononitrile, acetylenedicarboxylates and arylamines catalyzed by copper(i) iodide in aqueous medium under ultrasound irradiation has been
Pasha, M.A. +3 more
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Selective Mono Bromination of 1,4-Dihydropyridines [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1997 2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °C. The same reagent in dichloromethane at 0 °C produce the 2,6-
Yousef Rastgar Mirzaei +1 more
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Synthesis and antimicrobial evaluation of new 1,4-dihydro-4-pyrazolylpyridines and 4-pyrazolylpyridines [PDF]
, 2011 Background Dialkyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates (1,4-DHP) have now been recognized as vital drugs. Some of these derivatives such as amlodipine, felodipine, isradipine, etc. have been commercialized.
Om Prakash +5 more
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