Synthesis of Quinazoline and Quinazolinone Derivatives via Ligand-Promoted Ruthenium-Catalyzed Dehydrogenative and Deaminative Coupling Reaction of 2-Aminophenyl Ketones and 2-Aminobenzamides with Amines [PDF]
, 2019 The in situ formed ruthenium catalytic system ([Ru]/L) was found to be highly selective for the dehydrogenative coupling reaction of 2-aminophenyl ketones with amines to form quinazoline products.
Arachchige, Pandula T. Kirinde +1 more
core +3 more sources
The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis
Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio +2 more
wiley +2 more sources
Hantzsch Reaction Starting Directly from Alcohols through a Tandem Oxidation Process
Journal of Chemistry, 2017 A Brønsted acidic ionic liquid, 3-(N,N-dimethyldodecylammonium) propanesulfonic acid hydrogen sulphate ([DDPA][HSO4]), has been successfully applied to catalyze sequential oxidation of aromatic alcohols with NaNO3 followed by their condensation with ...
Xiaobing Liu, Bin Liu
doaj +1 more source
Journal of Pharmacy & Pharmaceutical Sciences, 2015 Years after the first report on 1,4-dihydropyridines (1,4-DHPs) and 1,2,3,4-tetrahydropyrimidines (1,2,3,4-THPMs) appeared, they are revisited as plausible therapeutic agents.
Saghi Sepehri +2 more
doaj +1 more source
Acta Biomedica Scientifica, 2023 Background. α-сyanothioacetamide derivatives are promising targets for the search for effective and safe antinociceptive agents with antipyretic and antiexudative activity. The aim. To conduct in vivo experimental study of anti-inflammatory and analgesic
I. V. Bibik +5 more
doaj +1 more source
Diethyl 2,6-Dimethyl-4-(naphthalen-1-yl)-1,4-Dihydropyridine-3,5-Dicarboxylate [PDF]
, 2016 In the title compound, C23H25NO4, the 1,4-dihydropyridine ring adopts a flattened boat conformation. The naphthalene ring system forms a dihedral angle of 88.59 (6)° with the pyridine ring.
Noor Shahina Begum, ., Prasad, N.L.
core +1 more source
TRPA1 channels: Novel targets of 1,4-dihydropyridines [PDF]
Channels, 2008 Transient receptor potential type A1 (TRPA1) channels are cation permeable channels activated by irritant chemicals and pungent natural compounds. Their location in peptidergic sensory terminals innervating the skin and blood vessels makes them important effectors of vasodilator responses of neural origin.
Fajardo, Otto +3 more
openaire +3 more sources
Simple Bronsted acid catalyzed C-H functionalization: efficient access to poly-substituted pyridines [PDF]
, 2016 An exceptionally simple and environmentally friendly methodology has been developed for directly functionalizing the benzylic C-H bond of the poly-substituted pyridines with aromatic imines.
Lai, SJ +6 more
core +1 more source
Antimicrobial Activity of Some Derivatives of 1,4-Dihydropyridines
Journal of Chemistry, 2013 Hantzsch reported the synthesis of functionalized 1,4-dihydropyridines via three-component condensation of an aromatic aldehyde, ketoester, and ammonium hydroxide.
Prabha Mehta, Prabha Verma
doaj +1 more source
One Pot Synthesis of Acridine Analogues from 1,2-Diols as Key Reagents [PDF]
, 2015 Lead tetraacetate have been demonstrated to be efficient, low cost and mild reagents for the one pot synthesis of acridine derivatives from a variety of 1,2-diols.
Jagadishbabu, N., Shivashankar, K.
core +1 more source