Results 71 to 80 of about 1,683 (133)
Metformin modifed UiO-66-NH<sub>2</sub> as a super basic nanocatalyst for the four component synthesis of dihydropyridines. [PDF]
Sci RepGhasempour L, Asghari S.
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Voltage-gated calcium channels as key regulators of neuronal differentiation in the immortalized dorsal root ganglion neuronal cell line F11. [PDF]
Sci RepLópez D +4 more
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Solid state photochemistry of 1,4-dihydropyridines
Bioorganic & Medicinal Chemistry Letters, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
Hamid R, Memarian, Arsalan, Mirjafari
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Coumarin 1,4-Dihydropyridine Derivatives
Bioorganic & Medicinal Chemistry, 1998A series of 1,4-dihydropyridines bearing a coumarin moiety in 4-position was synthesized. The compounds were evaluated for inotropic, chronotropic and calcium antagonist activities. The replacement of the o-nitrophenyl moiety of nifedipine with a coumarin or phenylcoumarin system is accompanied by a decrease of the activity on myocardial and vascular ...
Valenti P. +4 more
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Iodocyclization of 1,4-dihydropyridines
Tetrahedron Letters, 1998Abstract Iodine (or related species) addition to 1,4-dihydropyridines, with properly attached substituents at the nitrogen atom, leads to the corresponding 3-iodotetrahydropyridinium ions, which undergo an internal nucleophilic attack to furnish regio- and stereoselectively iodobi(poly)lteterocyclic ring systems in good yields.
Rodolfo Lavilla +3 more
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The oxidation of 1,4-dihydropyridines
Chemistry of Heterocyclic Compounds, 1970The olefinic bond of methenylbisindan-1,3-dione, 2-benzylideneindan-1, 3-dione, and its derivatives is easily reduced by many 1, 4-dihydropyridines. Under the conditions described, other functional groups are untouched. These Β-dicarbonyl compounds are utilized to compare the effects of substituents in 1,4-dihydropyridines on their reactivity in the ...
G. Ya. Dubur, Ya. R. Uldrikis
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1,4-Dihydropyridines and the 1,4-Dihydropyridine Receptor
1993The 1,4-dihydropyridine nifedipine is a first-generation drug of major significance in the treatment of cardiovascular disorders including hypertension, peripheral vascular disorders and angina in its several forms. Nifedipine is one of a chemically and pharmacologically heterogeneous group of drugs that includes also verapamil and diltiazem and which ...
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1,4-Dihydropyridine activators in the tiamdipine series
European Journal of Pharmacology, 1990The pharmacologic and radioligand binding properties of 5-nitro analogs of the 1,4-dihydropyridine Ca2+ channel antagonist, tiamdipine (2-(2-aminoethylthio)methyl-3-carbomethoxy-5-carbomethoxy-6-m ethyl-4-(3-nitrophenyl)-1,4-dihydropyridine) and its N-formyl derivative have been measured in rat tail artery, guinea pig ileum and rat heart.
GALLETTI, FERRUCCIO +2 more
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The photochemistry of 3,5-disubstituted 1,4-dihydropyridines
Tetrahedron, 1970Abstract On irradiation, 1,4-dihydropyridines have been shown to undergo three types of reaction: disproportionation, isomerization and dimerization. The presence of 2,6-substituents inhibits these reactions except in the case of 3a which undergoes disproportionation.
U, Eisner +3 more
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The 1,4-Dihydropyridine Receptor
Journal of Cardiovascular Pharmacology, 1984Evidence that nitrendipine (2,6-dimethyl-3-carbomethoxy-5-carbomethoxy-4-(3-nitrophenyl)1,4- dihydropyridine) and other 1,4-dihydropyridines interact at a specific site to antagonize Ca2+ channel function is reviewed. This evidence derives from electrophysiologic and pharmacologic studies and is confirmed by [3H]radioligand binding to excitable tissues.
D J, Triggle, R A, Janis
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