Results 61 to 70 of about 146,224 (211)
Dearomatization with Axial‐to‐Central Chirality Conversion
Atropisomers are exciting synthetic targets with unique properties, which find applications in many fields of chemistry. However, considering them as substrates is not very frequent, notably in the context of dearomatization reaction. We wish to discuss the different strategies for the dearomatization of aromatic atropisomers with axial‐to‐central ...
Morgane Mando +3 more
wiley +1 more source
Deciphering Small Molecule Diffusion Parameters Across Light Responsive Polymersome Membranes
Light‐responsive polymersomes bearing donor–acceptor Stenhouse adducts (DASAs) enable programmable control over small‐molecule transport across synthetic membranes. By systematically varying DASA density, an optimal functionalization regime is identified that maximizes light‐gated permeability.
Farzina Matubbar +7 more
wiley +1 more source
1,4-Dihydropyridines (DHPs) have been used in the reduction of carbon-carbon double bonds under microwave irradiation without solvent. The efficiency of the reactions is dramatically dependent on the steric effects in the DHPs and on the electronic ...
Jean Jacques Vanden Eynde +3 more
doaj +1 more source
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang +6 more
wiley +1 more source
Mimesis of dehydrogenase catalyzed reductions with chiral, bridged 1,4-dihydropyridines [PDF]
Het in dit proefschrift beschreven onderzoek was oorspronkelijk gericht op de volgende twee doeleinden: i. Het vinden van een bredere toepassing van 1,4-dihydropyridines die als modellen voor NADH beschouwd kunnen worden - als reductor in de organische ...
Vries, Johannes Gerardus de, +1 more
core +6 more sources
Mineralocorticoid receptor antagonists: Efficacy and safety in chronic kidney disease
Abstract The mineralocorticoid receptor (MR) has a multifaceted role in normal physiologic functions. However, research has uncovered the deleterious consequences of overactivation of the MR. It has been implicated in chronic kidney disease (CKD) via its strong association with glomerulosclerosis, interstitial fibrosis, proteinuria, and decline in ...
Amy K. Mottl +2 more
wiley +1 more source
Electrophilic Oxidative Additions upon 1,4-Dihydropyridines
Electrophilic Oxidative Additions upon 1,4 ...
Rakesh Kumar (8432) +3 more
core +1 more source
First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives
Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1,4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles in the presence of β-isocupreidine catalyst are reported.
Fernando Auria-Luna +2 more
doaj +1 more source
Organophotoredox/Cobalt‐Catalyzed Retro‐Hydroformylation of Aldehydes
A new photoredox/cobalt retro‐hydroformylation is developed. This one‐pot two‐step process involves the in situ formation of the corresponding 1,4‐dihydropyridine as key intermediate. Under mild reaction conditions, alkenes are efficiently produced from a wide range of aliphatic α‐monosubstituted aldehydes, with high functional‐group tolerance.
Augustin Nouaille +3 more
wiley +1 more source
The synthesis and in vitro calcium channel blocking activities and binding of 2-(ω- aminoalkylthiomethyl)-4-(substituted)phenyl-1,4-dihydropyridines, by determination of the displacement of [3H]nitrendipine from the calcium channel binding sites on rat ...
Christiaans, JAM +4 more
core +1 more source

