Results 61 to 70 of about 5,082 (203)

Catalytic Asymmetric Synthesis of Both Enantiomers of 4‑Substituted 1,4-Dihydropyridines with the Use of Bifunctional Thiourea-Ammonium Salts Bearing Different Counterions

Molecules, 2010
Organoammonium salts composed of a Brønsted acid and an anilinothiourea promoted the Michael addition of β-keto esters and α,β-unsaturated aldehydes in the presence of primary amines to give functionalized 1,4-dihydropyridines enantioselectively.
Kohzo Yoshida, Tsubasa Inokuma, Kiyosei Takasu, Yoshiji Takemoto   +3 more
doaj   +1 more source

Synthesis and chromatographic-separation of the stereoisomers of furnidipine [PDF]

, 1993
The four stereoisomers of methyl tetrahydrofuran-2-ylmethyl 2,6-dimethyl-4-(o-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxilate (furnidipine), have been synthesized and separated by chiral chromatography using D-phenylglycine as chiral stationary phase.
Alajarín Ferrández, Ramón, Casa-Juana Muñoz, Miguel Fau de, Sanz-Aparicio, Julia, Statkow, Peter R., Sunkel Letelier, Carlos, Vaquero López, Juan José, Álvarez-Builla Gómez, Julio   +6 more
core   +3 more sources

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

Advanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang, Junjie Cui, Zhenjie Yao, Boyuan Zhu, Nithinraj Panangattu Dharmarajan, Ajayan Vinu, Junwu Zhu   +6 more
wiley   +1 more source

Synthesis of bioorganometallic nanomolar-potent CB2agonists containing a ferrocene unit [PDF]

, 2016
A small library of ferrocene-containing amides has been synthesized using standard amide coupling chemistry with ferrocenylamine. Ferrocene analogues of known bioactive adamantylamides were shown to be effective cannabinoid receptor (CB1 and CB2 ...
Ahmedi R., Amélie Barczyk, Aurélien Tourteau, Felder C. C., Frédérique Klupsch, Graham J. Tizzard, John Spencer, Lucas Lemaire, Natascha Leleu-Chavain, Portier M., Rhee M. H., Rinaldi-Carmona M., Régis Millet, Simon J. Coles, Supojjanee Sansook, Wei Tuo, Xavier Dezitter, Zanoozi M.   +17 more
core   +3 more sources

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Synthesis of 2-Mono and 2,6-Disubstituted Methyl-1,4-Dihydropyridines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1997
The 2-mono and 2,6-disubstituted methyl-1,4-dihydropyridines were synthesized by reaction of morpholine, thiophenol, 8-hydroxyquinoline, 2-naphthol and 2-mercopto-1-methyl imidazole with the 2-mono bromo and 2,6-dibromo-1,4-dihidropyridines.
Yousef Rastgar Mirzaei, Karim Akbari Dilmaghani   +1 more
doaj  

Metabolism of the dihydropyridine calcium channel blockers mebudipine and dibudipine by isolated rat hepatocytes [PDF]

The prototype 1,4-dihydropyridine (1,4-DHP) nifedipine, indicated for the management of hypertension and angina pectoris, has drawbacks of rapid onset of vasodilating action and a short half-life.
Baarnhielm, Beresford, Borchard, Kobayashi, Mahmoudian, Mahmoudian, Mohri, Moldeus, Ramsch, Roden, Scherling, Scherling, Scherling, Stopher, Teramura, Van Zwieten   +15 more
core   +1 more source

Herbal therapy associated with antibiotic therapy: potentiation of the antibiotic activity against methicillin – resistant by L [PDF]

, 2009
Background Staphylococcus genus is widely spread in nature being part of the indigenous microbiota of skin and mucosa of animal and birds. Some Staphylococcus species are frequently recognized as etiological agents of many animal and human opportunistic ...
Henrique DM Coutinho, José GM Costa, Edeltrudes O Lima, Vivyanne S Falcão-Silva, José P Siqueira Júnior, A Nostro, MSV Pereira, J Verhoeff, D Karras, S Malhutra-Kumar, VA Roe, E Purssel, Y Lu, ZH Mbwambo, F Benoit-Vical, F Senatore, G Singh, S Gibbons, G Gunics, J Molnar, R Braga, M Pio Corrêa, KM Hosamani, MA Antonio, JS Gracioso, MA Nascimento, S Jana, E Smith, FI Freitas, BG Brasileiro, MM Javadpour, HDM Coutinho, FA Fryer, RM Perez, A Cáceres, JE Kristiansen, F Van Bambeke, G Gunics, Sh Hemaiswarya, H Wagner   +39 more
core   +2 more sources

Dearomatization with Axial‐to‐Central Chirality Conversion

European Journal of Organic Chemistry, EarlyView.
Atropisomers are exciting synthetic targets with unique properties, which find applications in many fields of chemistry. However, considering them as substrates is not very frequent, notably in the context of dearomatization reaction. We wish to discuss the different strategies for the dearomatization of aromatic atropisomers with axial‐to‐central ...
Morgane Mando, Clément Lemaitre, Thierry Constantieux, Xavier Bugaut   +3 more
wiley   +1 more source

Activation of Cyanate Anions by Phosphine Radical Cations Enables Formal Hydrocarbamoylation of Alkenes

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
A photocatalytic formal hydrocarbamoylation reaction that employs a cyanate anion as the C1 source and provides N‐acyl iminophosphorane products from activated alkenes is described. Mechanistic investigations suggest generation of a phosphoranyl radical by addition of the cyanate anion to a phosphine radical cation, which enables the delivery of the ...
Petra Vojáčková, Armido Studer
wiley   +2 more sources