Results 81 to 90 of about 1,683 (133)

Photoprotection of 1,4-dihydropyridine derivatives by dyes

International Journal of Pharmaceutics, 2005
The possibility of increasing the photochemical stability of nisoldipine by using indigotine and azorubine as photoprotectors has been studied. The course of the photodegradation was monitored by means of UV-vis spectrophotometry and HPLC. Quantitative assessments of the nisoldipine photodegradation included evaluation of the quantum yields and kinetic
Jadwiga, Mielcarek, Włodzimierz, Augustyniak, Paweł, Grobelny, Grazyna, Nowacka   +3 more
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Synthesis of Bis‐1,4‐dihydropyridine Derivatives.

ChemInform, 2005
Abstract A series of bis‐1,4‐dihydropyridine derivatives were synthesized by the reaction of p‐phenylenedialdehyde or m‐phenylenedialdehyde and active methylene compounds.
Songlei Zhu, Shujang Tu, Yuan Gao, Chunbao Miao, Tuanjie Li, Xiaojing Zhang, Fang Fang, Daqing Shi   +7 more
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Cocrystals of diastereoisomers of 1,4-dihydropyridine derivatives

Acta Crystallographica Section C Crystal Structure Communications, 2006
A mixture of the RR/SS and RS/SR diastereoisomeric pairs of methyl 4-(2,4-dichlorophenyl)-2,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, C 19 H 19 Cl 2 NO 3 , forms cocrystals in which there is one unique molecule in the asymmetric unit, but the molecule displays disorder in the region of the 7-position of the quinoline ring system as
Linden A, Gündüz MG, Simşek R, Safak C   +3 more
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Aromatization of 1,4‐Dihydropyridines with Selenium Dioxide.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Xiao-hua Cai, Hai-jun Yang, Guo-lin Zhang   +2 more
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1,4-Dihydropyridines bearing a pharmacophoric fragment of lidoflazine

Bioorganic & Medicinal Chemistry, 1996
A series of 1,4-dihydropyridines bearing a pharmacophoric fragment of lidoflazine was synthesized. The compounds were evaluated for inotropic, chronotropic, and calcium antagonist activities. All compounds behave as inotropic and chronotropic agents, except for compounds 4b, 5a, and 5b, which exhibit a rather weak calcium antagonism in vascular smooth ...
Chiarini A., Rampa A., Budriesi R., Bisi A., Fabbri G., Valenti P.   +5 more
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A new synthesis of 1,4-dihydropyridines

Journal of the Chemical Society, Perkin Transactions 1, 1975
The synthesis of 1,4-dihydropyridines unsubstituted in the 1-, 2-, and 6-positions from methyl propiolate, aromatic aldehydes, and ammonium acetate in acetic acid is described. The products were oxidised to the corresponding pyridines. Certain features of their n.m.r. spectra are discussed.
Tomy Chennat, Ulli Eisner
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Novel fluorescent 1,4-dihydropyridines

Journal of the American Chemical Society, 1986
Etude de la reaction modele de formation d'α-alkyl alkyl-4 diformyl-3,5 dihydro-1,4 pyridineacetates-1 a partir de propanedial, d'alcanals et d'α ...
Vasu. Nair, Rick J. Offerman, Gregory A. Turner   +2 more
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Metalation of 1,4-dihydropyridine esters

Tetrahedron Letters, 1989
Abstract 4-Aryl-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic esters are metalated at the NH and the C-2 methyl positions via tretament with two equivalents of n-butyl lithium. The resulting dilithio species can be treated with a variety of electrophiles to furnish C-2 methyl functionalized dihydropyridine esters.
Graham S. Poindexter, Michael A. Foley, Joseph F. Licause   +2 more
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The alkylation of hantzsch 1,4‐dihydropyridines

Journal of Heterocyclic Chemistry, 1986
AbstractThe reaction of carbanions derived from Hantzsch 1,4‐dihydropyridines with alkyl halides was studied and methods for mono‐ and di‐alkylation were devised.
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1,4-Dihydropyridine

Journal of the American Chemical Society, 1965
Newell C. Cook, James E. Lyons
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