Results 21 to 30 of about 146,224 (211)

New synthetic method for the synthesis of 1,4-dihydropyridine using aminated multiwalled carbon nanotubes as high efficient catalyst and investigation of their antimicrobial properties

Journal of Saudi Chemical Society, 2018
Synthesis of 1,4-dihydropyridines in the presence of aminated multiwalled carbon nanotubes and investigation into their antimicrobial properties were carried out.Amino functionalized carbon nanotubes were prepared through a facile, clean and safe ...
Roya Mahinpour, Leila Moradi, Zohreh Zahraei, Nafiseh Pahlevanzadeh   +3 more
doaj   +1 more source

SYNTHESIS AND PRELIMINARY ALKYLATING ACTIVITIES OF CERTAIN NEW 1,4-DIHYDROPYRIDINES, PYRIDINIUM SALTS AND 2,7-DIAZABICYCLO [4.1.0] HEPT-3-ENES [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 1993
3-Substituted-1-{2-chloro- or [2-bis (2-chloroethyl)amino]}ethyl-1,4-dihydropyridines 3 and 6 were prepared by reduction of the corresponding pyridinium chlorides 2 and 5 with sodium dithionite in alkaline medium.
Nawal El-Koussi, Mahmoud El-Gendy, Abdel-Alim Abdel-Alim, Hassan Farag   +3 more
doaj   +1 more source

Synthesis and anticholinesterase activity of a novel series of acetazolamide condensed 1,4-dihydropyridines

Carbon Resources Conversion, 2019
A novel Acetazolamide condensed 1, 4-dihydropyridines was set up by treating of N-(5-acetamido-1, 3, 4-thiadiazol-2-ylsulfonyl)-3-oxobutanamide with an aryl aldehyde and 25–30% alkali with sight amount of barium nitrate as a catalyst. Confirmation of the
Mudduluru Niranjan Babu, Karthikeyan Elumalai, Sivaneswari Srinivasan, Kalpana Eluri, Manogaran Elumalai, Srinivasan Sivannan   +5 more
doaj   +1 more source

Synthesis new fluorinated 4-phenyl-1,4-dihydropyridine derivatives, as perspective antiarrhythmic and antihypertensive drugs

Results in Chemistry, 2023
Derivatives of dihydropyridines are promising agents for research, as they have high biological activity. Their low toxicity and polytargeted properties make it possible to create new derivatives and identify new biological activity. As part of this work,
Arkadiy Bryzgalov, Tatiana Tolstikova, Borislav Koshcheev, Alexander Maksimov   +3 more
doaj   +1 more source

A Microwave-Assisted Bismuth Nitrate-Catalyzed Unique Route Toward 1,4-Dihydropyridines

Molecules, 2012
The classical Hantzsch reaction is one of the simplest and most economical methods for the synthesis of biologically important and pharmacologically useful 1,4-dihydropyridine derivatives.
Bimal K. Banik, Stephanie Maldonado, Debasish Bandyopadhyay   +2 more
doaj   +1 more source

Synthesis of Monofluoroalkenes through Visible-Light-Promoted Defluorinative Alkylation of gem-Difluoroalkenes with 4‑Alkyl-1,4-dihydropyridines

, 2020
In this study, a facile and efficient method to synthesize monofluoroalkenes by photoredox catalytic defluorinative alkylation of gem-difluoroalkenes with 4-alkyl-1,4-dihydropyridines under mild conditions (room temperature) is described.
Jing Sun (141206), He Wang (250350), Jing-Yun Wang (5645627), Ming-Dong Zhou (2362303), Qi-Sheng Gao (8364261), Hai-Wu Du (8364258), Zhaoqing Xu (1339896)   +6 more
core   +1 more source

Rearrangement of o-Nitrobenzaldehyde in the Hantzsch Reaction

Molecules, 2001
The reaction of 5-hydroxy-2-nitrobenzaldehyde with ethyl acetoacetate in ammonia gave the two expected isomeric 1,4- and 1,2-dihydropyridines resulting from the normal Hantzsch reaction.
R. Martínez, R. López- Castañares, A. Velázquez, A. Ramírez, I. Martínez, I. Menconi, H. Santillán, E. Angeles   +7 more
doaj   +1 more source

Selective Mono Bromination of 1,4-Dihydropyridines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1997
2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °C. The same reagent in dichloromethane at 0 °C produce the 2,6-
Yousef Rastgar Mirzaei, Adeleh Moshtaghi Zenouz   +1 more
doaj  

SYNTHESIS OF SOME 2,7-DIAZABICYCLO {4.l.0} HEPT-3-ENE DERIVATIVES WITH ANALGESIC AND ANTICOCCIDIAL ACTIVITY [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 1986
The 1,3-dipolar cycloaddition reaction of arylsulphonyl azides to 1,3-disubstituted-1,4-dihydropyridines afforded 2,7-diazabieyclo {4.1.0} hept-3-ene derivatives (III).These compounds exhibited more significant analgesic and anticoccidial activities than
A. El-Badr, R. Abdel-Aal, H. Hemaiat-Allah, H. Hassan, A. Abdel-Alim, H. Farag   +5 more
doaj   +1 more source

Organocatalytic Enantioselective Synthesis of 1,4‐Dihydropyridines [PDF]

Advanced Synthesis & Catalysis, 2017
AbstractThis review aims to bring light upon a very interesting group of compounds, the 1,4‐dihydropyridines (1,4‐DHPs). These structures are well‐known pharmacophores, used for many years to treat cardiovascular diseases because of their activity as calcium channel blockers.
Auria-Luna, Fernando, Marqués-López, Eugenia, Herrera, Raquel P.   +2 more
openaire   +2 more sources