Results 21 to 30 of about 116,777 (208)
Dually Acting Nonclassical 1,4-Dihydropyridines Promote the Anti-Tuberculosis (Tb) Activities of Clofazimine [PDF]
Molecules, 2019 The number of effective antituberculotic drugs is strongly limited to four first-line drugs in standard therapy. In case of resistances second-line antibiotics are used with a poor efficacy and tolerability.
Fabian Lentz +6 more
doaj +2 more sources
Synthesis of Some New Unsymmetrically Substituted 1,4-Dihydropyridines
Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences, 2006 A series of some new 3,5-unsymmetrically substituted 1,4-dihydropyridines have been synthesized, which have ethoxycarbonyl and acetyl groups on 3-and 5-positions, respectively. A three-step procedure has been examined to increase the yield of the desired
Hamid Reza Memarian +1 more
exaly +1 more source
AROMATIZATION OF 1,4-DIHYDROPYRIDINES WITH FREE RADICAL REAGENTS [PDF]
Journal of Sciences, Islamic Republic of Iran, 2001 Oxidation of different types of 1,4-dihydropyridines with diphenylpicrylhydrazyl (DPP) and benzoyl peroxide (Bz2O2) as free radical oxidizing agents to pyridine derivatives is reported and a mechanism for this oxidation is also proposed.
doaj +1 more source
Chemistry Proceedings, 2023 Hantzsch 1,4-dihydropyridines (Hantzsch 1,4-DHP), have been utilized as starting material in organic synthesis. In addition, several 1,4-DHP based drugs (Nifedipine, Niguldipine, Amlodepine besylate) have been recognized for the treatment of ...
Juan Enrique Tacoronte Morales +4 more
doaj +1 more source
Radical‐Based C−C Bond‐Forming Processes Enabled by the Photoexcitation of 4‐Alkyl‐1,4‐dihydropyridines [PDF]
Angewandte Chemie - International Edition, 2017 Luca Buzzetti +2 more
exaly +2 more sources
1,4-Dihydropyridines as Alkyl Radical Precursors: Introducing the Aldehyde Feedstock to Nickel/Photoredox Dual Catalysis [PDF]
ACS Catalysis, 2016 John C Tellis +2 more
exaly +2 more sources
Beilstein Journal of Organic Chemistry, 2023 The three-component reaction of isoquinolines, dialkyl acetylenedicarboxylates, and 5,6-unsubstituted 1,4-dihydropyridines in acetonitrile at room temperature afforded functionalized isoquinolino[1,2-f][1,6]naphthyridines in good yields and with high ...
Xiu-Yu Chen +4 more
doaj +1 more source
Transition-Metal-Free Alkylation and Acylation of Benzoxazinones with 1,4-Dihydropyridines
, 2021 The direct functionalization of N-heterocycles is a vital transformation for the development of pharmaceuticals, functional materials, and other chemical entities.
Prithwish Ghosh (7122755) +13 more
core +2 more sources
Cobalt-Catalyzed Selective Dearomatization of Pyridines to N–H 1,4-Dihydropyridines
, 2022 Catalytic reduction of pyridines to N–H 1,4-dihydropyridines is exceptionally challenging because they are essential intermediates to form tetrahydropyridines.
Lan Liu (88052) +15 more
core +1 more source
Organocatalytic Enantioselective Synthesis of 1,4‐Dihydropyridines [PDF]
Advanced Synthesis & Catalysis, 2017 AbstractThis review aims to bring light upon a very interesting group of compounds, the 1,4‐dihydropyridines (1,4‐DHPs). These structures are well‐known pharmacophores, used for many years to treat cardiovascular diseases because of their activity as calcium channel blockers.
Auria-Luna, Fernando +2 more
openaire +2 more sources