Results 111 to 120 of about 10,563,202 (308)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Creative problem-solving assessment and product design education
, 2018 This study reports findings from the administration of Creative Engineering Design Assessment (CEDA) to product design. The aim is to assess the applicability of CEDA in this discipline for the analysis of students’ level of creative problem-solving (CPS)
Oraklıbel, R. D. +2 more
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Toward proactive eco-design based on engineer and eco-designer's software interface modeling [PDF]
, 2011 Lien vers la version éditeur: http://www.designsociety.org/publication/30585/toward_proactive_eco-design_based_on_engineer_and_eco-designers_software_interface_modelingIntegrating environmental concerns as well as other constrains (cost, quality, etc ...
RIO, Maud +2 more
core
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Preliminary of User Interface Design for Picture Archiving and Communication System
, 2013 [[abstract]]In order to gain entry to modern and technology, medical imaging technology not only has to economically storing, and conveniently accessing, images from multiple modalities, but also focus on user’s experience and interaction.
Lin, Wei-Chun Winine;Lee, Yuan-Zone
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Design Research and Public Policy: Current Practice Working to Intersect with Government
, 2014 Design research is an academic and practical field of study that seeks to explore the ways in which design in any discipline area is produced, understood, and used.
Parliamentary Design and Innovation Group, All Party
core
IEEE Journal of MicrowavesThis paper introduces a rapid filter synthesis method that utilizes the improved Chebyshev function to design versatile broadband on-chip filters with multiple (N) independently controlled transmission zeros (TZs). It eliminates the constraints of narrow
Xiaolong Huang +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source