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Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Synthetic worlds, synthetic strategies: attaining creativity in the metaverse [PDF]
This text will attempt to delineate the underlying theoretical premises and the definition of the output of an immersive learning approach pertaining to the visual arts to be implemented in online, three dimensional synthetic worlds.
Ayiter, Elif
core
Synthetic Biology and Synthetic Knowledge [PDF]
Probably the most distinctive feature of synthetic biology is its being “synthetic” in some sense or another. For some, synthesis plays a unique role in the production of knowledge that is most distinct from that played by analysis: it is claimed to deliver knowledge that would otherwise not be attained.
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Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Synthetic magnetism for photon fluids [PDF]
We develop a theory of artificial gauge fields in photon fluids for the cases of both second-order and third-order optical nonlinearities. This applies to weak excitations in the presence of pump fields carrying orbital angular momentum, and is thus a ...
Faccio, D.+5 more
core +4 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Learning from Synthetic Data Using a Stacked Multichannel Autoencoder
Learning from synthetic data has many important and practical applications. An example of application is photo-sketch recognition. Using synthetic data is challenging due to the differences in feature distributions between synthetic and real data, a ...
Agam, Gady+4 more
core +1 more source
Environmental effects of natural dyes and syntetic dyes: a comparison [PDF]
Dyes is important to add colorant on fabrics. The dyeing process makes a fabric colourful and attractive. However, the waste disposed by dyeing process was hazard to environment especially synthetic dyes.
Jalil, Anis Jazira+3 more
core
Synthetic listeners and synthetic performers [PDF]
Each partner in a collaborative music performance must also be an expert listener. Several “performers” have been built for a variety of musical situations, and each given a listening skill that permits it to substitute for a human performer. This typically entails real-time pitch detection of an instrument or voice, matching the events heard against ...
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