Results 1 to 10 of about 239,193 (302)

Synthetic Ionizable Colloidal Drug Aggregates Enable Endosomal Disruption [PDF]

open access: yesAdvanced Science, 2023
Colloidal drug aggregates enable the design of drug‐rich nanoparticles; however, the efficacy of stabilized colloidal drug aggregates is limited by entrapment in the endo‐lysosomal pathway.
Eric N. Donders   +6 more
doaj   +4 more sources

Synthetic Soil Aggregates: Bioprinted Habitats for High-Throughput Microbial Metaphenomics

open access: yesMicroorganisms, 2022
The dynamics of microbial processes are difficult to study in natural soil, owing to the small spatial scales on which microorganisms operate and to the opacity and chemical complexity of the soil habitat.
Darian Smercina   +7 more
doaj   +3 more sources

Synthetic Aggregates for the Production of Innovative Low Impact Porous Layers for Urban Pavements

open access: yesInfrastructures, 2019
According to the latest estimates, 40% of urban areas are covered by pavements. One of the most remarkable effects on the urban environment is the increase in impermeable surfaces which leads to problems related to water infiltration into the ground and ...
Piergiorgio Tataranni, Cesare Sangiorgi
doaj   +3 more sources

Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods [PDF]

open access: yesActa Neuropathologica Communications, 2018
The concept that abnormal protein aggregates show prion-like propagation between cells has been considered to explain the onset and progression of many neurodegenerative diseases.
Airi Tarutani   +4 more
doaj   +3 more sources

Detection of extracellular amyloid beta aggregates by an Aducanumab-based synNotch receptor: an in vitro proof-of-concept study [PDF]

open access: yesJournal of Translational Medicine
Background Synthetic Notch (synNotch) receptors are a powerful gene regulation platform that activate transcription in response to membrane-bound ligands and extracellular matrix components, with emerging applications in cancer, autoimmunity, and ...
Nicholas J. Bergo   +5 more
doaj   +2 more sources

Lysozyme Amyloid for Synthetic RNA Delivery [PDF]

open access: yesPharmaceutics
Background/Objectives: Lysozyme-based amyloid aggregates offer a promising platform for RNA delivery due to their stability, cationic nature, biocompatibility, and ability to form well-defined structures.
Benjamin Beluzo   +4 more
doaj   +2 more sources

New insights into the production of sustainable synthetic aggregates and their microstructural evaluation

open access: yesMateriales de Construccion, 2023
In this study, a novel technique for producing synthetic aggregates using industrial by-products was experimentally investigated. Taguchi method is used to identify the optimum mix design proportion to develop durable synthetic aggregates.
R. Vignesh, A. Abdul-Rahim
doaj   +1 more source

Stereochemistry‐Controlled Supramolecular Architectures of New Tetrahydroxy‐Functionalised Amphiphilic Carbocyanine Dyes [PDF]

open access: yes, 2020
The syntheses of novel amphiphilic 5,5′,6,6‐tetrachlorobenzimidacarbocyanine (TBC) dye derivatives with aminopropanediol head groups, which only differ in stereochemistry (chiral enantiomers, meso form and conformer), are reported.
Berlepsch, Hans von   +6 more
core   +1 more source

Sustainable shotcrete production with waste glass aggregates

open access: yesSN Applied Sciences, 2022
Article highlights This study investigates sand replacement with glass aggregates in shotcrete production for use in excavation industry. Tested shotcrete mixes containing glass aggregates exhibited a similar or higher strength properties at both early ...
Mehdi Serati   +4 more
doaj   +1 more source

GRAPE: A Stochastic Geometrical 3D Model for Aggregates of Particles With Tunable 2D Morphological Projected Properties

open access: yesImage Analysis and Stereology, 2023
The main goal of this paper is to propose a method for the 3D morphological characterization of compact aggregates using 2D image analysis. The problem at hand is the 3D morphometric characterization of latex nanoparticle aggregates.
Leo Theodon   +2 more
doaj   +1 more source

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