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The Role of Synthetic Biology in NASA's Missions [PDF]
The time has come to for NASA to exploit the nascent field of synthetic biology in pursuit of its mission, including aeronautics, earth science, astrobiology and notably, human exploration.
Rothschild, Lynn J.
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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The Regulatory Network of Transcription Factors in Macrophage Polarization
ImmunoTargets and TherapyJie Liu,1,2 Mengran Wang,1,2 Yong Zhao1,2 1State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People’s Republic of ...
Liu J, Wang M, Zhao Y
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Electron Microscopy Analysis of Multilamellar Vesicles Prepared from Synthetic Lipids: A Model System for Studying Membrane Structure in the Molecular Cell Biology Classroom and Laboratory [PDF]
, 2004 Russell R. Camp +2 more
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BBF RFC 108: Synthetic Biology Open Language (SBOL) Version 2.0.0 [PDF]
, 2015 The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing ...
Bartley, Bryan +14 more
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The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
FEBS Letters, EarlyView.The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
Comparative genomics reveals the origin of fungal hyphae and multicellularity
Nature Communications, 2019 Hyphae are a major innovation in fungi associated with transitions to multicellularity. Here, Kiss and colleagues use comparative genomic analyses to reconstruct the evolutionary origins of hyphae and the molecular evolution of hypha morphogenesis genes.
Enikő Kiss +12 more
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Synthetic models in biology are artifacts constructed from biological components, such as genes and proteins, to form biological parts or wholes. They have the same materiality as natural biological systems but are not the results of natural evolutionary processes.
Knuuttila, Tarja, Loettgers, Andrea
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FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Meeting Report: Synthetic Biology Jamboree for Undergraduates [PDF]
, 2005 A. Malcolm Campbell
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