Results 121 to 130 of about 2,829,869 (398)
Building biosecurity for synthetic biology
Molecular Systems Biology, 2020 The fast‐paced field of synthetic biology is fundamentally changing the global biosecurity framework. Current biosecurity regulations and strategies are based on previous governance paradigms for pathogen‐oriented security, recombinant DNA research, and ...
Benjamin D. Trump +16 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Between the possible and the actual: Philosophical perspectives on the design of synthetic organisms
, 2013 International audienceA number of research projects in synthetic biology funded by public institutions sound like science fiction: for instance DARPA Biodesign project in 2011 aimed at eliminating "the randomness of natural evolutionary advancement, and ...
Bensaude-Vincent, Bernadette
core +2 more sources
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Awareness of and Attitudes Toward Nanotechnology and Synthetic Biology [PDF]
, 2008 Based on a survey and focus groups, examines Americans' awareness of nanotechnology and synthetic biology, their initial impressions, and their assessments of the tradeoffs between the potential benefits and ...
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Plant chemical genetics : from phenotype-based screens to synthetic biology [PDF]
, 2017 The treatment of a biological system with small molecules to specifically perturb cellular functions is commonly referred to as chemical biology. Small molecules are used commercially as drugs, herbicides, and fungicides in different systems, but in ...
Dejonghe, Wim, Russinova, Eugenia
core +3 more sources
Cell-Free Protein Synthesis as a Prototyping Platform for Mammalian Synthetic Biology.
ACS Synthetic Biology, 2020 The field of mammalian synthetic biology is expanding quickly, and technologies for engineering large synthetic gene circuits are increasingly accessible. However, for mammalian cell engineering, traditional tissue culture methods are slow and cumbersome,
Margarita B. Kopniczky +9 more
semanticscholar +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Synthetic biology—putting engineering into biology [PDF]
, 2017 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias, Panke, Sven
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