Results 151 to 160 of about 916,052 (349)

Large-scale genomic rearrangements boost SCRaMbLE in Saccharomyces cerevisiae

Nature Communications
Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) is a promising tool to study genomic rearrangements. However, the potential of SCRaMbLE to study genomic rearrangements is currently hindered, because a strain ...
Li Cheng, Shijun Zhao, Tianyi Li, Sha Hou, Zhouqing Luo, Jinsheng Xu, Wenfei Yu, Shuangying Jiang, Marco Monti, Daniel Schindler, Weimin Zhang, Chunhui Hou, Yingxin Ma, Yizhi Cai, Jef D. Boeke, Junbiao Dai   +15 more
doaj   +1 more source

Erratum: Corrigendum: Synthetic fluorescent sensors for studying the cell biology of metals [PDF]

, 2008
Dylan W. Domaille, Emily L. Que, Christopher J. Chang   +2 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Storage‐D: A user‐friendly platform that enables practical and personalized DNA data storage

iMeta
Deoxyribonucleic acid (DNA) has been suggested as a very promising medium for data storage in recent years. Although numerous studies have advocated for DNA data storage, its practical application remains obscure and there is a lack of a user‐oriented ...
Xiaoluo Huang, Junting Cui, Wei Qiang, Jianwen Ye, Yu Wang, Xinying Xie, Yuanzhen Li, Junbiao Dai   +7 more
doaj   +1 more source

Ensuring the security of synthetic biology—towards a 5P governance strategy [PDF]

, 2009
Alexander Kelle
openalex   +1 more source

Synthetic Biology Open Language (SBOL) Version 1.1.0 [PDF]

, 2012
In this BioBricks Foundation Request for Comments (BBF RFC), we specify the Synthetic Biology Open Language (SBOL) Version 1.1.0 to enable the electronic exchange of information describing DNA components used in synthetic biology. We define: 1.
Adam, Laura, Adler, Aaron, Anderson, J. Christopher, Beal, Jacob, Cai, Yizhi, Chandran, Deepak, Densmore, Douglas, Drory, Omri A., Endy, Drew, Galdzicki, Michal, Gennari, John H., Grünberg, Raik, Ham, Timothy S., Hillson, Nathan J., Johnson, Jeffrey D., Kuchinsky, Allan, Lux, Matthew W., Madsen, Curtis, Misirli, Goksel, Myers, Chris J., Oberortner, Ernst, Olguin, Carlos, Peccoud, Jean, Plahar, Hector, Platt, Darren, Pocock, Matthew R., Rodriguez, Cesar A., Roehner, Nicholas, Sauro, Herbert M., Sirin, Evren, Smith, Trevor F., Stan, Guy-Bart, Villabos, Alan, Wilson, Mandy, Wipat, Anil   +34 more
core  

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Synthetic biology [PDF]

Nature Biotechnology, 2019
openaire   +2 more sources

Van Regenmortel M.H.V., Muller S., Synthetic peptides as antigens. Laboratory techniques in biochemistry and molecular biology, van der Vliet P.C. (Ed.), Elsevier, 1999.

, 2000
P Meyer
openalex   +1 more source

A synthetic-biology reality check [PDF]

, 2009
Erika Check Hayden, Heidi Ledford
openalex   +1 more source