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Synthetic Biology—The Synthesis of Biology

Angewandte Chemie - International Edition, 2017
AbstractSynthetic biology concerns the engineering of man‐made living biomachines from standardized components that can perform predefined functions in a (self‐)controlled manner. Different research strategies and interdisciplinary efforts are pursued to implement engineering principles to biology.
Martin Fussenegger, David Auslander
exaly   +5 more sources

Evolution and synthetic biology

Current Opinion in Microbiology, 2023
Evolutionary observations have often served as an inspiration for biological design. Decoding of the central dogma of life at a molecular level and understanding of the cellular biochemistry have been elegantly used to engineer various synthetic biology applications, including building genetic circuits in vitro and in cells, building synthetic ...
Marya Y, Ornelas   +3 more
openaire   +2 more sources

The Impact of Synthetic Biology

ACS Synthetic Biology, 2013
Synthetic biology has recently been at the center of the world's attention as a new scientific and engineering discipline. It allows us to design and construct finely controllable metabolic and regulatory pathways, circuits, and networks, as well as create new enzymes, pathways, and even whole cells.
Gi Na, Lee, Jonguk, Na
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Synthetic Biology

2018
Synthetic biology advances upon genetic engineering. It makes use of engineering principles and methods such as rational design and modularity, and it includes inserting synthetically produced genetic sequences or whole genomes that code for novel intracellular pathways into organisms.
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The limits of synthetic biology

Trends in Biotechnology, 2015
The pioneering works of Watson, Crick, Wilkins, and Franklin [1,2] on the structure of DNA have captivated our imaginations for over half a century and continue to shape our future endeavors. The genetic code, a mystery for many years, was soon thereafter decoded by organic chemists employing organic synthesis of polynucleotides [3].
Bijan, Zakeri, Peter A, Carr
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Synthetic Biology of Yeast

Biochemistry, 2019
With the rapid development of DNA synthesis and next-generation sequencing, synthetic biology that aims to standardize, modularize, and innovate cellular functions, has achieved vast progress. Here we review key advances in synthetic biology of the yeast Saccharomyces cerevisiae, which serves as an important eukaryal model organism and widely applied ...
Zihe Liu, Yueping Zhang, Jens Nielsen
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Standardization in Synthetic Biology

2011
Synthetic Biology is founded on the idea that complex biological systems are built most effectively when the task is divided in abstracted layers and all required components are readily available and well-described. This requires interdisciplinary collaboration at several levels and a common understanding of the functioning of each component ...
Müller, Kristian M.   +3 more
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Synthetic biology I

Proceedings of the 11th Annual Conference Companion on Genetic and Evolutionary Computation Conference: Late Breaking Papers, 2009
This talk is divided to two parts. First comes Dr. Luc Varin with an introduction to the molecular biology fundamentals necessary for the full appreciation of the second part given by Dr. Nawwaf Kharma. He will will speak about the use of Synthetic Biology ideas and methods to build computational devices, with the aim of building larger and more ...
Nawwaf Kharma, Luc Varin
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