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Chemical Reviews
Cells contain thousands of different lipids. Their rapid and redundant metabolism, dynamic movement, and many interactions with other biomolecules have justly earned lipids a reputation as a vexing class of molecules to understand. Further, as the cell's hydrophobic metabolites, lipids assemble into supramolecular structures─most commonly bilayers, or ...
Po-Hsun Brian Chen +2 more
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Cells contain thousands of different lipids. Their rapid and redundant metabolism, dynamic movement, and many interactions with other biomolecules have justly earned lipids a reputation as a vexing class of molecules to understand. Further, as the cell's hydrophobic metabolites, lipids assemble into supramolecular structures─most commonly bilayers, or ...
Po-Hsun Brian Chen +2 more
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Synthetic Biology—The Synthesis of Biology
Angewandte Chemie International Edition, 2017AbstractSynthetic biology concerns the engineering of man‐made living biomachines from standardized components that can perform predefined functions in a (self‐)controlled manner. Different research strategies and interdisciplinary efforts are pursued to implement engineering principles to biology.
Simon Ausländer +2 more
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2018
Synthetic biology advances upon genetic engineering. It makes use of engineering principles and methods such as rational design and modularity, and it includes inserting synthetically produced genetic sequences or whole genomes that code for novel intracellular pathways into organisms.
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Synthetic biology advances upon genetic engineering. It makes use of engineering principles and methods such as rational design and modularity, and it includes inserting synthetically produced genetic sequences or whole genomes that code for novel intracellular pathways into organisms.
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ACS Synthetic Biology, 2013
Synthetic biology is frequently defined as the application of engineering design principles to biology. Such principles are intended to streamline the practice of biological engineering, to shorten the time required to design, build, and test synthetic gene networks. This streamlining of iterative design cycles can facilitate the future construction of
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Synthetic biology is frequently defined as the application of engineering design principles to biology. Such principles are intended to streamline the practice of biological engineering, to shorten the time required to design, build, and test synthetic gene networks. This streamlining of iterative design cycles can facilitate the future construction of
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Current Opinion in Biotechnology, 2001
Synthesis of data into formal models of cellular function is rapidly becoming a necessary industry. The complexity of the interactions among cellular constituents and the quantity of data about these interactions hinders the ability to predict how cells will respond to perturbation and how they can be engineered for industrial or medical purposes ...
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Synthesis of data into formal models of cellular function is rapidly becoming a necessary industry. The complexity of the interactions among cellular constituents and the quantity of data about these interactions hinders the ability to predict how cells will respond to perturbation and how they can be engineered for industrial or medical purposes ...
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Evolutionary Synthetic Biology
ACS Synthetic Biology, 2012Signaling networks process vast amounts of environmental information to generate specific cellular responses. As cellular environments change, signaling networks adapt accordingly. Here, I will discuss how the integration of synthetic biology and directed evolution approaches is shedding light on the molecular mechanisms that guide the evolution of ...
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Engineering living therapeutics with synthetic biology
Nature Reviews Drug Discovery, 2021Andres Cubillos-Ruiz +2 more
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