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Special Milk and Synthetic Biology: A Dual-Perspective Review of Ingredient Substitutions in Breast-Milk-Simulated Infant Formula. [PDF]
Compr Rev Food Sci Food SafZhang C +7 more
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The Challenges Facing Synthetic Biology in Eukaryotes
Nature Reviews Molecular Cell Biology, 2018 Synthetic biology is maturing into a true engineering discipline for model microorganisms, but remains far from straightforward for most eukaryotes. Here, we outline the key challenges facing those trying to engineer biology across eukaryota and suggest ...
Thomas Ellis, Francesca Ceroni
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Synthetic Biology to Access and Expand Nature's Chemical Diversity [PDF]
Nature Reviews Microbiology, 2016 Bacterial genomes encode the biosynthetic potential to produce hundreds of thousands of complex molecules with diverse applications, from medicine to agriculture and materials.
Jan Claesen, Michael J Smanski, Ben Shen
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Synthetic Biology—The Synthesis of Biology
Angewandte Chemie International Edition, 2017AbstractSynthetic biology concerns the engineering of man‐made living biomachines from standardized components that can perform predefined functions in a (self‐)controlled manner. Different research strategies and interdisciplinary efforts are pursued to implement engineering principles to biology.
Simon Ausländer +2 more
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Biochemistry, 2019
With the rapid development of DNA synthesis and next-generation sequencing, synthetic biology that aims to standardize, modularize, and innovate cellular functions, has achieved vast progress. Here we review key advances in synthetic biology of the yeast Saccharomyces cerevisiae, which serves as an important eukaryal model organism and widely applied ...
Zihe Liu, Yueping Zhang, Jens Nielsen
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With the rapid development of DNA synthesis and next-generation sequencing, synthetic biology that aims to standardize, modularize, and innovate cellular functions, has achieved vast progress. Here we review key advances in synthetic biology of the yeast Saccharomyces cerevisiae, which serves as an important eukaryal model organism and widely applied ...
Zihe Liu, Yueping Zhang, Jens Nielsen
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The Impact of Synthetic Biology
ACS Synthetic Biology, 2013Synthetic biology has recently been at the center of the world's attention as a new scientific and engineering discipline. It allows us to design and construct finely controllable metabolic and regulatory pathways, circuits, and networks, as well as create new enzymes, pathways, and even whole cells.
Gi Na, Lee, Jonguk, Na
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2018
Synthetic biology advances upon genetic engineering. It makes use of engineering principles and methods such as rational design and modularity, and it includes inserting synthetically produced genetic sequences or whole genomes that code for novel intracellular pathways into organisms.
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Synthetic biology advances upon genetic engineering. It makes use of engineering principles and methods such as rational design and modularity, and it includes inserting synthetically produced genetic sequences or whole genomes that code for novel intracellular pathways into organisms.
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The Plant Journal, 2013
SummaryPlastids (chloroplasts) harbor a small gene‐dense genome that is amenable to genetic manipulation by transformation. During 1 billion years of evolution from the cyanobacterial endosymbiont to present‐day chloroplasts, the plastid genome has undergone a dramatic size reduction, mainly as a result of gene losses and the large‐scale transfer of ...
Scharff, L., Bock, R.
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SummaryPlastids (chloroplasts) harbor a small gene‐dense genome that is amenable to genetic manipulation by transformation. During 1 billion years of evolution from the cyanobacterial endosymbiont to present‐day chloroplasts, the plastid genome has undergone a dramatic size reduction, mainly as a result of gene losses and the large‐scale transfer of ...
Scharff, L., Bock, R.
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Synthetic biology and healthcare
Emerging Topics in Life Sciences, 2019Through the application of the engineering paradigm of ‘design–build–test–learn’ allied to recent advances in DNA sequencing, bioinformatics and, critically, the falling cost of DNA synthesis, Synthetic Biology promises to make existing therapies more accessible and be at the centre of the development of new types of advanced therapies.
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Standardization in Synthetic Biology
2011Synthetic Biology is founded on the idea that complex biological systems are built most effectively when the task is divided in abstracted layers and all required components are readily available and well-described. This requires interdisciplinary collaboration at several levels and a common understanding of the functioning of each component ...
Müller, Kristian M. +3 more
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