Results 251 to 260 of about 3,570,847 (308)

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

The plant Golden Gate toolkit: compatibility, interoperability, and harmonized assembly in plant synthetic biology. [PDF]

Plant Methods
Bélanger JG, Hanaishi S, Péret B.
europepmc   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Amalgamation of Biofilms and Synthetic Biology: A Paradigm Shift in Biotechnology. [PDF]

Med Princ Pract
Bhamidipaty DL, Bhamidipaty V, Shaikh FM, Bhamidipaty KDP, Botchu R.   +4 more
europepmc   +1 more source

Betacyanin biofortification in wheat via synthetic biology for nutritional enhancement. [PDF]

Plant Physiol
Peng H, Huang W, Wang S, Han Z, Li X, Tang H, Ye X, Lu Y, Xu L, Wang K.   +9 more
europepmc   +1 more source

Synthetic soils for ecological and synthetic biology applications. [PDF]

FEMS Microbiol Rev
Orebaugh J, Carrell AA, York LM, Cregger MA, Del Valle Kessra I.   +4 more
europepmc   +1 more source

Tumor-Mimic Artificial Cell Integrated With In Situ Synthetic Biology for Testing of Antitumor Drug Sensitivity. [PDF]

Exploration (Beijing)
Guan C, Zhang R, Zhou Z, Sun P, Mao Y, Mao C, Ma Y, Chen G, Man Q, Feng C.   +9 more
europepmc   +1 more source

Recent technology advancements in large‐scale DNA assembly

Quantitative Biology
Jielin Li, Li Cheng, Yingxin Ma, Yizhi Cai, Junbiao Dai   +4 more
doaj   +1 more source

Improving governance in the age of synthetic biology, artificial intelligence, and diverging threats. [PDF]

Front Bioeng Biotechnol
Sabra DM, Frieß JL, Giese B, Jeremias G.   +3 more
europepmc   +1 more source