Results 231 to 240 of about 3,570,847 (308)

Leveraging the bacteria for enhanced cancer immunotherapy: from a perspective of synthetic biology. [PDF]

Cancer Biol Ther
Liu X, Zhang H, Du R, Liu Z, Ren Y, Yang X.   +5 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Engineered bacterial therapeutics from synthetic biology to clinical translation: A multi-database scientometric analysis, 2000-2026. [PDF]

Hum Vaccin Immunother
Zhou H, He J, Chen J, Ge S, Yu P, Zhang W.   +5 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Intracellularly Coupled Oscillators for Synthetic Biology [PDF]

Nat Commun
Holló G, Park JH, Evard R, Schaerli Y.
europepmc   +2 more sources

The Landscape of Synthetic Biology and Bioengineering in Spain. [PDF]

Eng Biol
Rivas G, Otero-Muras I, de Lorenzo V.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Engineering next-generation CAR-NK cells for hematological malignancies: genome editing, synthetic biology, and precision immunotherapy. [PDF]

Front Genome Ed
Bahr AR, Basem Y, Alhejely A, Alaa AR, Abozeid SM, Basem A, Khormi MA, Abo-Zaid MA.   +7 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Assessing the inhibition efficacy of clinical drugs against the main proteases of SARS‐CoV‐2 variants and other coronaviruses

Quantitative Biology
Wenlong Zhao, Cecylia S. Lupala, Shifeng Hou, Shuxin Yang, Ziqi Yan, Shujie Liao, Xuefei Li, Nan Li   +7 more
doaj   +1 more source