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Synthetic Biology—The Synthesis of Biology
Angewandte Chemie - International Edition, 2017AbstractSynthetic biology concerns the engineering of man‐made living biomachines from standardized components that can perform predefined functions in a (self‐)controlled manner. Different research strategies and interdisciplinary efforts are pursued to implement engineering principles to biology.
Simon Auslander, Martin Fussenegger
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Biochemistry, 2019
With the rapid development of DNA synthesis and next-generation sequencing, synthetic biology that aims to standardize, modularize, and innovate cellular functions, has achieved vast progress. Here we review key advances in synthetic biology of the yeast Saccharomyces cerevisiae, which serves as an important eukaryal model organism and widely applied ...
Zihe Liu, Yueping Zhang, Jens Nielsen
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With the rapid development of DNA synthesis and next-generation sequencing, synthetic biology that aims to standardize, modularize, and innovate cellular functions, has achieved vast progress. Here we review key advances in synthetic biology of the yeast Saccharomyces cerevisiae, which serves as an important eukaryal model organism and widely applied ...
Zihe Liu, Yueping Zhang, Jens Nielsen
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The Impact of Synthetic Biology
ACS Synthetic Biology, 2013Synthetic biology has recently been at the center of the world's attention as a new scientific and engineering discipline. It allows us to design and construct finely controllable metabolic and regulatory pathways, circuits, and networks, as well as create new enzymes, pathways, and even whole cells.
Gi Na, Lee, Jonguk, Na
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Nature Biotechnology, 2006
RNA molecules play important and diverse regulatory roles in the cell by virtue of their interaction with other nucleic acids, proteins and small molecules. Inspired by this natural versatility, researchers have engineered RNA molecules with new biological functions.
Farren J, Isaacs +2 more
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RNA molecules play important and diverse regulatory roles in the cell by virtue of their interaction with other nucleic acids, proteins and small molecules. Inspired by this natural versatility, researchers have engineered RNA molecules with new biological functions.
Farren J, Isaacs +2 more
openaire +2 more sources
BMJ, 2010
May hinder future research and restrict access to innovation The recent report from the J Craig Venter Institute of the engineering of a self replicating bacterium with a chemically synthesised genome is a step towards artificial life and raises potential ethical concern.1 “Synthetic biology” has emerged in recent years as an umbrella term to ...
Sarah, Chan, John, Sulston
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May hinder future research and restrict access to innovation The recent report from the J Craig Venter Institute of the engineering of a self replicating bacterium with a chemically synthesised genome is a step towards artificial life and raises potential ethical concern.1 “Synthetic biology” has emerged in recent years as an umbrella term to ...
Sarah, Chan, John, Sulston
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2018
Synthetic biology advances upon genetic engineering. It makes use of engineering principles and methods such as rational design and modularity, and it includes inserting synthetically produced genetic sequences or whole genomes that code for novel intracellular pathways into organisms.
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Synthetic biology advances upon genetic engineering. It makes use of engineering principles and methods such as rational design and modularity, and it includes inserting synthetically produced genetic sequences or whole genomes that code for novel intracellular pathways into organisms.
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Synthetic biology and healthcare
Emerging Topics in Life Sciences, 2019Through the application of the engineering paradigm of ‘design–build–test–learn’ allied to recent advances in DNA sequencing, bioinformatics and, critically, the falling cost of DNA synthesis, Synthetic Biology promises to make existing therapies more accessible and be at the centre of the development of new types of advanced therapies.
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Standardization in Synthetic Biology
2011Synthetic Biology is founded on the idea that complex biological systems are built most effectively when the task is divided in abstracted layers and all required components are readily available and well-described. This requires interdisciplinary collaboration at several levels and a common understanding of the functioning of each component ...
Müller, Kristian M. +3 more
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Trends in Biotechnology, 2004
Synthetic biology is advancing rapidly as biologists, physicists and engineers are combining their efforts to understand and program cell function. By characterizing isolated genetic components or modules, experimentalists have paved the way for more quantitative analyses of genetic networks.
William J, Blake, Farren J, Isaacs
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Synthetic biology is advancing rapidly as biologists, physicists and engineers are combining their efforts to understand and program cell function. By characterizing isolated genetic components or modules, experimentalists have paved the way for more quantitative analyses of genetic networks.
William J, Blake, Farren J, Isaacs
openaire +2 more sources