Results 91 to 100 of about 457,590 (279)

Synthetic Training Data for CT Image Segmentation of Microstructures

Acta Materialia
The segmentation of images obtained through techniques such as computed tomography is a key step in generating digital twins of porous microstructures. A common approach to segmentation is the use of supervised machine learning algorithms, such as U-Net.
Lars Griem, Arnd Koeppe, Alexander Greß, Thomas Feser, Britta Nestler   +4 more
openaire   +3 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Toward Closing the Loop in Image-to-Image Conversion in Radiotherapy: A Quality Control Tool to Predict Synthetic Computed Tomography Hounsfield Unit Accuracy

Journal of Imaging
In recent years, synthetic Computed Tomography (CT) images generated from Magnetic Resonance (MR) or Cone Beam Computed Tomography (CBCT) acquisitions have been shown to be comparable to real CT images in terms of dose computation for radiotherapy ...
Paolo Zaffino, Ciro Benito Raggio, Adrian Thummerer, Gabriel Guterres Marmitt, Johannes Albertus Langendijk, Anna Procopio, Carlo Cosentino, Joao Seco, Antje Christin Knopf, Stefan Both, Maria Francesca Spadea   +10 more
doaj   +1 more source

Synthetic CT Generation from MRI Using Improved DualGAN

, 2019
Synthetic CT image generation from MRI scan is necessary to create radiotherapy plans without the need of co-registered MRI and CT scans. The chosen baseline adversarial model with cycle consistency permits unpaired image-to-image translation. Perceptual loss function term and coordinate convolutional layer were added to improve the quality of ...
Prokopenko, Denis, Stadelmann, Joël Valentin, Schulz, Heinrich, Renisch, Steffen, Dylov, Dmitry V.   +4 more
openaire   +2 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis–Associated Interstitial Lung Disease Risk

Arthritis Care &Research, EarlyView.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase‐7 (MMP‐7), and serum anti–malondialdehyde‐acetaldehyde (anti‐MAA) antibody for rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) risk stratification.
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients with Extra‐Renal Systemic Lupus Erythematosus – A Systematic Review & Meta‐analysis

Arthritis Care &Research, Accepted Article.
Background Clinical response to Mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with SLE, particularly those with extra‐renal ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Optimizing thoracic synthetic computed tomography generation from magnetic resonance imaging: the role of Fourier transform and other key factors

Physics and Imaging in Radiation Oncology
Background and purpose: Magnetic Resonance Imaging-only (MRI-only) workflows are an emerging strategy in radiotherapy, with artificial intelligence (AI) playing a central role in generating synthetic computed tomography (sCT) images. The thorax remains a
Alessandro Bombini, Luca Vellini, Flaviovincenzo Quaranta, Jacopo Lenkowicz, Sebastiano Menna, Elisa Pilloni, Francesco Catucci, Andrea D’Aviero, Claudio Votta, Giuditta Chiloiro, Martina Iezzi, Francesco Preziosi, Alessia Re, Althea Boschetti, Floranna Mauro, Sami Aburas, Lana Smiljanic, Antonio Piras, Carmela Di Dio, Lorenzo Placidi, Luca Boldrini, Maria Antonietta Gambacorta, Gian Carlo Mattiucci, Davide Cusumano   +23 more
doaj   +1 more source

A Multi-center Prospective Study for Implementation of an MRI-Only Prostate Treatment Planning Workflow

Frontiers in Oncology, 2019
Purpose: This project investigates the feasibility of implementation of MRI-only prostate planning in a prospective multi-center study.Method and Materials: A two-phase implementation model was utilized where centers performed retrospective analysis of ...
Peter Greer, Peter Greer, Jarad Martin, Jarad Martin, Mark Sidhom, Mark Sidhom, Perry Hunter, Peter Pichler, Jae Hyuk Choi, Leah Best, Joanne Smart, Tony Young, Tony Young, Michael Jameson, Michael Jameson, Michael Jameson, Michael Jameson, Tess Afinidad, Chris Wratten, Chris Wratten, James Denham, James Denham, Lois Holloway, Lois Holloway, Lois Holloway, Swetha Sridharan, Robba Rai, Robba Rai, Robba Rai, Gary Liney, Gary Liney, Gary Liney, Parnesh Raniga, Jason Dowling, Jason Dowling, Jason Dowling   +35 more
doaj   +1 more source