Results 51 to 60 of about 457,590 (279)

Improved Color-Temperature Relations and Bolometric Corrections for Cool Stars

open access: yes, 1999
We present new grids of colors and bolometric corrections for F-K stars having 4000 K < Teff < 6500 K, 0.0 < log g < 4.5 and -3.0 < [Fe/H] < 0.0. A companion paper extends these calculations into the M giant regime.
A. V. Sweigart   +44 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

A Comparison of Cosmological Models Using Time Delay Lenses

open access: yes, 2014
The use of time-delay gravitational lenses to examine the cosmological expansion introduces a new standard ruler with which to test theoretical models. The sample suitable for this kind of work now includes 12 lens systems, which have thus far been used ...
Melia, Fulvio   +2 more
core   +1 more source

Cepstral analysis based on the Glimpse proportion measure for improving the intelligibility of HMM-based synthetic speech in noise [PDF]

open access: yes, 2012
In this paper we introduce a new cepstral coefficient extraction method based on an intelligibility measure for speech in noise, the Glimpse Proportion measure.
King, S.   +4 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Improvement of Quantification of Myocardial Synthetic ECV with Second-Generation Deep Learning Reconstruction

open access: yesJournal of Cardiovascular Development and Disease
Background: The utility of synthetic ECV, which does not require hematocrit values, has been reported; however, high-quality CT images are essential for accurate quantification.
Tsubasa Morioka   +9 more
doaj   +1 more source

Synthetic CT generation for MRI-guided adaptive radiotherapy in prostate cancer

open access: yesFrontiers in Oncology, 2022
Current MRI-guided adaptive radiotherapy (MRgART) workflows require fraction-specific electron and/or mass density maps, which are created by deformable image registration (DIR) between the simulation CT images and daily MR images.
Shu-Hui Hsu   +5 more
doaj   +1 more source

A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers. [PDF]

open access: yes, 2019
Cohesin is a multiprotein ring that is responsible for cohesion of sister chromatids and formation of DNA loops to regulate gene expression. Genomic analyses have identified that the cohesin subunit STAG2 is frequently inactivated by mutations in cancer.
Ashworth, Alan   +4 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Spatial resolution enhancement using deep learning improves chest disease diagnosis based on thick slice CT

open access: yesnpj Digital Medicine
CT is crucial for diagnosing chest diseases, with image quality affected by spatial resolution. Thick-slice CT remains prevalent in practice due to cost considerations, yet its coarse spatial resolution may hinder accurate diagnoses.
Pengxin Yu   +23 more
doaj   +1 more source

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