Results 51 to 60 of about 462,780 (278)

Racial and Gender Wage Differentials in South Africa: What can Cohort Data tell? [PDF]

, 2003
Three subsequent years of the October Household Survey data are used to construct a synthetic panel. Preparing cross sectional data that way allows to better utilise individual information and to address temporal developments also in the absence of ...
Grün, Carola
core   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Improvement of Quantification of Myocardial Synthetic ECV with Second-Generation Deep Learning Reconstruction

Journal of Cardiovascular Development and Disease
Background: The utility of synthetic ECV, which does not require hematocrit values, has been reported; however, high-quality CT images are essential for accurate quantification.
Tsubasa Morioka, Shingo Kato, Ayano Onoma, Toshiharu Izumi, Tomokazu Sakano, Eiji Ishikawa, Shungo Sawamura, Naofumi Yasuda, Hiroaki Nagase, Daisuke Utsunomiya   +9 more
doaj   +1 more source

Synthetic CT generation for MRI-guided adaptive radiotherapy in prostate cancer

Frontiers in Oncology, 2022
Current MRI-guided adaptive radiotherapy (MRgART) workflows require fraction-specific electron and/or mass density maps, which are created by deformable image registration (DIR) between the simulation CT images and daily MR images.
Shu-Hui Hsu, Zhaohui Han, Jonathan E. Leeman, Yue-Houng Hu, Raymond H. Mak, Atchar Sudhyadhom   +5 more
doaj   +1 more source

Improved Color-Temperature Relations and Bolometric Corrections for Cool Stars

, 1999
We present new grids of colors and bolometric corrections for F-K stars having 4000 K < Teff < 6500 K, 0.0 < log g < 4.5 and -3.0 < [Fe/H] < 0.0. A companion paper extends these calculations into the M giant regime.
A. V. Sweigart, Bell K. L., Bell R. A., Bell R. A., Bell R. A., Bell R. A., Bessell M. S., Biemont E., Biemont E., Biemont E., Blackwell D. E., Blackwell D. E., Blackwell D. E., Bonnell J. T., Bonnell J. T., Buser R., Charbonnel C., Charbonnel C., Chevalier C., Cousins A. W. J., Davis D. S., Di Benedetto G. P., Doughty N. A., Edvardsson B., Engels D., Glass I. S., Gratton R. G., Gustafsson B., Gustafsson B., Holweger H., Johnson H. L., Kjaergaard P., M. L. Houdashelt, Meynet G., Nordstrom B., O’Brian T. R., Paltoglou G., Pauls T. A., Perrin G., R. A. Bell, Ramsauer J., Rufener F., Saxner M., Solanki S. K., Taylor B. J.   +44 more
core   +2 more sources

Cepstral analysis based on the Glimpse proportion measure for improving the intelligibility of HMM-based synthetic speech in noise [PDF]

, 2012
In this paper we introduce a new cepstral coefficient extraction method based on an intelligibility measure for speech in noise, the Glimpse Proportion measure.
King, S., Maia, R., Valentini-Botinhao, C., Yamagishi, J., Zen, H.   +4 more
core   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Spatial resolution enhancement using deep learning improves chest disease diagnosis based on thick slice CT

npj Digital Medicine
CT is crucial for diagnosing chest diseases, with image quality affected by spatial resolution. Thick-slice CT remains prevalent in practice due to cost considerations, yet its coarse spatial resolution may hinder accurate diagnoses.
Pengxin Yu, Haoyue Zhang, Dawei Wang, Rongguo Zhang, Mei Deng, Haoyu Yang, Lijun Wu, Xiaoxu Liu, Andrea S. Oh, Fereidoun G. Abtin, Ashley E. Prosper, Kathleen Ruchalski, Nana Wang, Huairong Zhang, Ye Li, Xinna Lv, Min Liu, Shaohong Zhao, Dasheng Li, John M. Hoffman, Denise R. Aberle, Chaoyang Liang, Shouliang Qi, Corey Arnold   +23 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Radiation-free diagnosis of lumbar spondylolysis: case series evaluating MRI-based synthetic CT efficacy

The Egyptian Journal of Radiology and Nuclear Medicine
Background Computed tomography (CT) is favored for diagnosing lumbar spondylolysis owing to its high resolution, rapid scanning, and cost-effectiveness.
Gan Cao, Jichao Zhu, Anyu Yin, Shanghuang Xie, Xiaolin Yang, Helin Liu, Feiyuan Zhang, Ling Luo, Zhaotong Li, Jun Xia   +9 more
doaj   +1 more source