PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Synthetic CT Image Generation From CBCT: A Systematic Review
IEEE Transactions on Radiation and Plasma Medical Sciences21 pages, 14 Figures, Accepted in the IEEE Transactions on Radiation and Plasma Medical ...
Alzahra Altalib +3 more
openaire +3 more sources
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Physics and Imaging in Radiation Oncology, 2020 Background and purpose: Magnetic Resonance (MR)-only planning has been implemented clinically for radiotherapy of prostate cancer. However, fewer studies exist regarding the overall success rate of MR-only workflows. We report on successes and challenges
Neelam Tyagi +8 more
doaj +1 more source
Effect of synthetic and bovine milk conjugated linoleic acid (CLA) on immune function : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition Science at Massey University [PDF]
, 1999 CLA is a collective name for a mixture of positional and geometrical isomers of linoleic acid (c-9, c-12-octadecadioenic acid) which possess conjugated double bonds.
Zhao, Hui
core
Forward Attention in Sequence-to-sequence Acoustic Modelling for Speech Synthesis
, 2018 This paper proposes a forward attention method for the sequenceto- sequence acoustic modeling of speech synthesis. This method is motivated by the nature of the monotonic alignment from phone sequences to acoustic sequences. Only the alignment paths that
Dai, Li-Rong +2 more
core +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Inductive Visual Localisation: Factorised Training for Superior Generalisation [PDF]
, 2018 End-to-end trained Recurrent Neural Networks (RNNs) have been successfully applied to numerous problems that require processing sequences, such as image captioning, machine translation, and text recognition.
Gupta, Ankush +2 more
core +2 more sources
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Clustered Multitask Nonnegative Matrix Factorization for Spectral Unmixing of Hyperspectral Data
, 2019 In this paper, the new algorithm based on clustered multitask network is proposed to solve spectral unmixing problem in hyperspectral imagery. In the proposed algorithm, the clustered network is employed.
Khoshsokhan, Sara +2 more
core +1 more source