Results 181 to 190 of about 2,406,574 (279)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Opinion: Mental health research: to augment or not to augment

Frontiers in Psychiatry
Argyrios Perivolaris, Alice Rueda, Karisa Parkington, Achint Soni, Sirisha Rambhatla, Sirisha Rambhatla, Reza Samavi, Rakesh Jetly, Andrew Greenshaw, Yanbo Zhang, Bo Cao, Bo Cao, Bo Cao, Sri Krishnan, Venkat Bhat, Venkat Bhat   +15 more
doaj   +1 more source

Digital Metrology for Nanoindentation: Synthetic Data Generator for Error Identification. [PDF]

Micromachines (Basel)
Maculotti G, Giorio L, Genta G, Galetto M.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

MetaAcuPoint: MetaHuman-Generated Synthetic Data for Hand Acupoint Localization. [PDF]

Healthcare (Basel)
Guruge K, Padmanabha P, Herath HMKKMB, Madusanka N, Park HJ, Na CS, Yi M, Lee BI.   +7 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Evaluation of Cerebral Blood Flow and Cerebral Autoregulation Using Synthetic Data and In Silico Modeling. [PDF]

CNS Neurosci Ther
Bozkurt S.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

An ELIXIR scoping review on domain-specific evaluation metrics for synthetic data in life sciences. [PDF]

NAR Genom Bioinform
Fragkouli SC, Iqbal S, Crossman L, Gravel B, Masued N, Onders M, Haseja D, Stikkelman A, Valencia A, Lenaerts T, Psomopoulos F, Ó Broin P, Queralt-Rosinach N, Cirillo D.   +13 more
europepmc   +1 more source