Results 71 to 80 of about 262,774 (333)

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, EarlyView.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Seropositivity of syphilis among individuals screened in a tertiary hospital in the Eastern Province of Saudi Arabia

Annals of Saudi Medicine, 2021
BACKGROUND: Sexually transmitted infections are a serious public health problem. Syphilis, a multistage, curable chronic disease caused by the spirochete Treponema pallidum, remains a major health problem worldwide.
Nahid H. O. Wanni, Reem Al Dossary, Obeid E. Obeid, Nourah Hasan Al Qahtani, Zaheenul Islam Siddiqui, Ayman A. El-Badry, Khaled R. Alkharsah   +6 more
doaj   +1 more source

Maternal Gestational Low‐Grade Inflammation and the Risk of Anorexia Nervosa in Daughters

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Prenatal exposures have been suggested to have a programming effect on neural and metabolic development, which may affect the risk of eating disorders. We investigated the association between prospectively measured maternal gestational high‐sensitivity C‐reactive protein (hs‐CRP), an established inflammatory biomarker, and subsequent
Emma Saure, Pyry N. Sipilä, Cynthia M. Bulik, Elina Santti, Heljä‐Marja Surcel, Antti Latvala, Anu Raevuori   +6 more
wiley   +1 more source

Immunophenotypic variations in syphilis: insights from Mendelian randomization analysis

Frontiers in Immunology
BackgroundInfection with Treponema pallidum instigates complex immune responses. Prior research has suggested that persistent Treponema pallidum infection can manipulate host immune responses and circumvent host defenses.
Qinghui Xie, Yijie Tang, Lingyun Shen, Dandan Yang, Jiaqin Zhang, Qingqiong Luo   +5 more
doaj   +1 more source

Syphilis among Female Sex Workers: Results of Point-of-Care Screening during a Cross-Sectional Behavioral Survey in Burkina Faso, West Africa

International Journal of Microbiology, 2018
Background. Syphilis among female sex workers (FSW) remains a public health concern due to its potential impact on their health and the possibility of transmission to their clients, partners, and children. Recent data on the prevalence of syphilis in the
Henri Gautier Ouedraogo, Ivlabehire Bertrand Meda, Issaka Zongo, Odette Ky-Zerbo, Ashley Grosso, Benoit Cesaire Samadoulougou, Grissoum Tarnagda, Kadari Cisse, Apoline Sondo, Nongoba Sawadogo, Yves Traoré, Nicolas Barro, Stefan Baral, Seni Kouanda   +13 more
doaj   +1 more source

Trends in HIV prevalence and risk behaviours among men who have sex with men from 2013 to 2017 in Nanjing, China: a consecutive cross-sectional survey. [PDF]

, 2019
OBJECTIVE:To examine the trends of HIV prevalence, risk behaviours and HIV testing among men who have sex with men (MSM) in Nanjing. DESIGN:Five consecutive cross-sectional surveys. SETTING:Nanjing, China.
Detels, Roger, Li, Xin, Liu, Li, Wu, Sushu, Xu, Fei, Xu, Wenjiong, Xu, Yuanyuan, Yan, Hongjing, Zhu, Zhengping   +8 more
core   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Serological Tests Of Syphilis In HIV Infection [PDF]

, 2005
Serological tests for syphilis may show varying results in association with HIV infection.Thus care should be taken to interpret these ...
Bhat M, Dr. Ramesh
core  

Demographic and Behavioural Factors in Tanzanian and Norwegian Patients with Sexually Transmitted Infections. [PDF]

, 2006
To evaluate whether differences in demographic or behavioural factors might explain differences in reported or diagnosed sexually transmitted infections (STI), we have compared data from 1097 Tanzanian and Norwegian STI patients.
Chalamila, Guerino, Haarr, Lars, Langeland, Nina, Matre, Roald, Mwakagile, Davis, Nilsen, Arvid   +5 more
core   +1 more source

The limits of women's choices in Japan: Pronatalism, autonomy, and narratives of sexual risk in the era of the pill

Feminist Anthropology, EarlyView.
Abstract The continued assault on women's reproductive freedoms has dampened the critique of the liberal feminist logics of autonomy in reproductive rights activism. This article centers on the Pill, a longtime symbol of women's empowerment, to reorient debates about individual choice.
S. Y. Cheung
wiley   +1 more source