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Syphilis is a sexually transmitted infection (STI) caused by the spiral bacterium Treponema pallidum. Diagnosis is based on epidemiology, clinical and serology, but serodiagnosis is challenging because distinct clinical forms of the infection may ...
Ângelo Antônio Oliveira Silva +15 more
doaj +1 more source
Background: The lack of Treponema pallidum-specific antigens with highly accurate diagnosis makes the diagnosis of syphilis challenging. Methods: A soluble recombinant version of a new diagnostic protein Tp0663 has been produced.
Man Xu +11 more
doaj +1 more source
Acroangiodermatitis (pseudo-Kaposi's sarcoma) in an HIV sero-positive patient with syphilis and hepatitis C virus coinfection: clinical and dermatopathological features [PDF]
Acroangiodermatitis is an angioproliferative disease usually related to chronic venous insufficiency, and it is considered a clinical and histological simulator of Kaposi's sarcoma (KS).
Fred Bernardes Filho +4 more
doaj +2 more sources
Diagnostically significant antigens of Treponema pallidum subsp. pallidum: identification, serological efficacy, and characterisation of the major antigenic determinants. [PDF]
The antibody response to native antigens derived from Treponema pallidum (Nichols strain) was investigated by western blotting. In early primary disease the responses were most frequently to the major immunodominant antigen, TpN47, and the flagellar ...
Grace, Christopher
core +1 more source
A sífilis, doença de importante morbiletalidade no passado, tem ressurgido nos últimos anos, graças, sobretudo, às alterações nos comportamentos de risco.
Fabricio Cecanho Furlan +5 more
doaj +1 more source
One of the modifications of Wassermann's reaction, Katzr's method, is known to focus on complement by titrating it per se in the presence of normal serum, syphilitic antigen, and antigen together with normal serum.
openaire +1 more source
Impact of Chlamydia trachomatis in the reproductive setting: British Fertility Society Guidelines for practice [PDF]
Chlamydia trachomatis infection of the genital tract is the most common sexually transmitted infection and has a world-wide distribution. The consequences of infection have an adverse effect on the reproductive health of women and are a common cause of ...
Adams E.J. +92 more
core +2 more sources
OBJECTIVE: Programmes to control syphilis in developing countries are hampered by a lack of laboratory services, delayed diagnosis, and doubts about current screening methods. We aimed to compare the diagnostic accuracy of an immunochromatographic strip (
Montoya Pablo J +6 more
doaj
Borrelia Burgdorferi-specific IgA in Lyme Disease [PDF]
The laboratory diagnosis of Lyme disease is currently dependent on the detection of IgM and IgG antibodies against Borrelia burgdorferi, the causative agent of the disease. The significance of serum IgA against B. burgdorferi remains unclear.
Arnaboldi, Paul +2 more
core +3 more sources
Background. The enzyme-linked immunosorbent assay based on recombinant analogues of Treponema pallidum immunogenic proteins enables the diagnosis of syphilis by determining immunoglobulin G and immunoglobulin M. The detection of specific immunoglobulin M
N. V. Arbuzova +3 more
doaj +1 more source

