Results 71 to 80 of about 19,151 (222)

HIV Services Implementation Within US Syringe Services Programs: A Qualitative Exploration

AIDS Patient Care and STDs
The recent rise in HIV incidence among people who inject drugs in the United States highlights an urgent need to improve HIV testing, treatment linkage, and pre-exposure prophylaxis access in this group. Syringe services programs (SSPs) play a critical role by offering or linking clients to these services, yet little is known about how such care is ...
Alexis M. Roth, Elana Forman, Christopher F. Akiba, William H. Eger, Rose Laurano, Shelby L. Huffaker, Sheila V. Patel, Jessica Smith, Barrot H. Lambdin, Angela R. Bazzi   +9 more
openaire   +2 more sources

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

Advanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte, Marshall S. Padilla, Elisa Battistini, Hannah M. Yamagata, Violet M. Ullman, Alex Chan, Benjamin E. Nachod, Anushka Agrawal, Maxwell B. Watkins, Jesse B. Hopkins, Andrew Tsourkas, Kushol Gupta, Michael J. Mitchell   +14 more
wiley   +1 more source

Feasibility of paying people who use drugs cash to distribute naloxone within their networks

Harm Reduction Journal
Introduction Immediate access to naloxone is needed to prevent fatal opioid-related overdoses in the presence of fentanyl analogs saturating the opioid supply. Peer models engage impacted populations who are not accessing naloxone through standard venues,
Nikki M. Lewis, Rebecca P. Smeltzer, Trevor J. Baker, Andrea C. Sahovey, Justine Baez, Erika Hensel, Brandon Poole, Cecelia Stewart, Allyson G. Cogan, Mackenzie Bullard, Jessica L. Taylor   +10 more
doaj   +1 more source

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

Advanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu, Bin Cui, Xumin Huang, Xiaoyu (Rayne) Zheng, T. Thang Vo‐Doan, Ruirui Qiao   +5 more
wiley   +1 more source

Funding and Delivery of Syringe Services Programs in the United States, 2022

American Journal of Public Health
Objectives. To describe the current financial health of syringe services programs (SSPs) in the United States and to assess the predictors of SSP budget levels and associations with delivery of public health interventions. Methods. We surveyed all known SSPs operating in the United States from February to June 2022 (n = 456), of which 68% responded ...
Shelley N. Facente, Jamie L. Humphrey, Christopher Akiba, Sheila V. Patel, Lynn D. Wenger, Hansel Tookes, Ricky N. Bluthenthal, Paul LaKosky, Stephanie Prohaska, Terry Morris, Alex H. Kral, Barrot H. Lambdin   +11 more
openaire   +4 more sources

3D‐Printing Aided Rapid Prototyping of Pretensioned Tensegrity Structures for Robotic Applications

Advanced Robotics Research, EarlyView.
Printing, injection molding, and assembly (PMA) is a method for rapid prototyping mesoscale, topologically complex, and tensioned tensegrity structures. In combination with PMA method, two mold design strategies: modular mold and compact channel layout, enable efficiency and scalability for tensegrity fabrication.
Yi Sun, Jan Petrš, Omar Aloui, Dario Floreano   +3 more
wiley   +1 more source

Improving equity and access to buprenorphine treatment through telemedicine at syringe services programs

Substance Abuse Treatment, Prevention, and Policy, 2022
Abstract Background and aims In the United States, access to buprenorphine remains low and disparities regarding who receives treatment have emerged. Federal laws have regulated buprenorphine delivery, ultimately limiting its implementation more broadly.
Barrot H. Lambdin, David Kan, Alex H. Kral   +2 more
openaire   +3 more sources

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Implementation determinants of safer smoking supplies in U.S. syringe services programs [PDF]

Implementation Science Communications
Abstract Background The prevalence of smoking opioids and other unregulated drugs has increased across the United States (U.S.) since 2000. Improved access to safer smoking supplies may reduce the health consequences of inhalation while helping to engage more people who use drugs in syringe services programs (SSPs ...
William H. Eger, Angel K. Gomez, Kirstin Kielhold, Tyler S. Bartholomew, Angela R. Bazzi   +4 more
openaire   +3 more sources

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source