Results 41 to 50 of about 303,922 (266)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
RRAM Crossbar-Based In-Memory Computation of Anisotropic Filters for Image Preprocessingloa
IEEE Access, 2020 Anisotropic-diffusion is a commonly used signal preprocessing technique that allows extracting meaningful local characteristics from a signal, such as edges in an image and can be used to support higher-level processing tasks, such as shape detection ...
Fakhreddine Zayer +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sensors, 2018 Herein, we present a low-power cyclic Vernier two-step time-to-digital converter (TDC) that achieves a wide input range with good linearity. Since traditional approaches require a large area or high power to achieve an input range >300 ns, we solve ...
Van Nhan Nguyen +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Self-Awareness in Systems on Chip— A Survey [PDF]
IEEE Design & Test, 2017 Published in IEEE Design & ...
Axel Jantsch +2 more
openaire +4 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Efficient memristor accelerator for transformer self-attention functionality
Scientific ReportsThe adoption of transformer networks has experienced a notable surge in various AI applications. However, the increased computational complexity, stemming primarily from the self-attention mechanism, parallels the manner in which convolution operations ...
Meriem Bettayeb +4 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Brain inspired iontronic fluidic memristive and memcapacitive device for self-powered electronics
Microsystems & NanoengineeringIonic fluidic devices are gaining interest due to their role in enabling self-powered neuromorphic computing systems. In this study, we present an approach that integrates an iontronic fluidic memristive (IFM) device with low input impedance and a ...
Muhammad Umair Khan +4 more
doaj +1 more source