Results 171 to 180 of about 28,064,677 (308)

Black-hole system: in vivo continuous bioligand-assisted elimination of circulating tumor cells to prevent cancer recurrence and metastasis. [PDF]

Microsyst Nanoeng
Abdulla A, Chen R, Yan H, Su H, Shi Y, He S, Ding J, Yu K, Abudureheman T, Qu H, Yang M, Wu S, Chen Z, Jiang L, Ding X.   +14 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The University of Texas System Administration: Annual FInancial Report (with detailed supportive schedules) Unaudited, Fiscal Year Ended August 31, 2011

, 2011
Annual financial report by The University of Texas System Administration documenting income, expenditures, and other relevant financial information for fiscal year ...
University of Texas System
core  

The Estimated Health System Cost Impacts of Interventions to Reduce Alcohol Harm in New Zealand: A Modelling Study. [PDF]

Drug Alcohol Rev
Mizdrak A, Davies A, Cobiac L, Chambers T.   +3 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

What we can learn about biology from monogenic diseases; KIF11 and the glymphatic and lymphatic-like system of the retina and choroid and its possible role in the pathogenesis of pachychoroid and central serous chorioretinopathy. [PDF]

Int J Retina Vitreous
Pulido JS, Arevalo JF, Farrell LC, Muste JC.   +3 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

OTHER TITLE: Child Welfare System Task Force final report

, 2019
At head of page O-1: Child Welfare System Task Force final report. "January 2019."Committee Reports to the Kansas Legislature ; 2019."House Sub. for SB 126 (2017) directs the Secretary for Children and Families to establish a Child Welfare System ...
Kansas. Child Welfare System Task Force.
core  

Smart Emergency Assistance System With Pre-Entry Access for Older Adults Living Alone: Simulation-Based Implementation Report. [PDF]

JMIR Form Res
Chen JY, Lu KD, Cai YJ, Li YL, Shen FY, Ji L, Lu FY.   +6 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source