Results 181 to 190 of about 34,241,884 (316)

New strategies for mitigating undesirable odors connected to geosmin and 2-MIB in minced fish muscle: a model system approach. [PDF]

Sci Rep
Phetsang H, Chaijan M, Panpipat W, Undeland I.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

AI-LyD: An AI-Driven System Approach to Combatting Spotted Lanternfly Proliferation Through Behavioral Analysis. [PDF]

Insects
Zhang K.
europepmc   +1 more source

Orthopedics and Traumatology Skill Matrix for Musculoskeletal System Approach by Medical Graduates. [PDF]

Rev Bras Ortop (Sao Paulo), 2023
Siqueira EM, Pereira AA, Oliveira IAKM.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Assessing the demand for cigarettes and e-cigarettes among US adult e-cigarette users: a cross-sectional study using a demand system approach. [PDF]

BMJ Public Health
Xu L, Zhang Z, Shang C.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Safe system approach to preventing cyclist fatalities: safety by design for urban and rural environments. [PDF]

Inj Epidemiol
Charyk Stewart T, Pellar A, Halari M, McClafferty K, Verville P, Pickup M, Fraser D, Gilliland J, Shkrum M.   +8 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Component-Based Approach in Learning Management System Development

The paper describes component-based approach (CBA) for learning management system development. Learning object as components of e-learning courses and their metadata is considered.
Bule, Jekaterina, Zaiceva, Larisa, Makarovs, Sergejs   +2 more
core