Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Perspectives in Pediatric Ambulatory Anesthesia: Part 4-Evolving Solutions in Pediatric Ambulatory Anesthesia: From Registries to a Learning Health System Approach. [PDF]
Olbrecht VA, Martin LD.
europepmc +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
An Approach of the Grey System Modelling and Simulation for Complex Systems
There has been a long histroy of the System Dynamics developed by J.Forrester and its analysis of complex system behaviors. It is necessary to know the detailed system structure and a large amount statistical data to build the flow diagram when using ...
Zhang, Lu, Yi YW(易允文)
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A learning health system approach to improving chronic kidney disease management in primary care. [PDF]
Thatcher EJ +6 more
europepmc +1 more source
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley +1 more source
An abductive inferential system approach to weight of evidence syntheses: the problem and military exposures worked example. [PDF]
Parrott JS +11 more
europepmc +1 more source
Sociotechnical Work System Approach to Occupational Fatigue. [PDF]
Watterson TL +5 more
europepmc +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Annual; Dec. 31, 2002-; Title varies slightly.; Vol. for 2003- are for the years ended Dec. 31, 2003 & 2002-; Prepared under the direction of the OPERS Finance Division.; Harvested from the web on 7/25 ...
Ohio Public Employees Retirement System.
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