Results 151 to 160 of about 5,197,383 (319)
Preliminary Study on Deterministic Chaotic System From Physical Approach [PDF]
, 2019 Chaotic phenomenon widely exists in the nonlinear dynamic systems. Such phenomenon is described to be highly related the initial conditions and intrinsic system properties. Traditionally, large effort has been put on evaluation of the existence of chaos,
Zhao, Lihua
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
System approach and the classification of bibliography functions in document-centrist paradigm
Библиосфера, 2014 The results of developing the document-centrist paradigm in bibliogragraphy are summed up, its main methodological advances are stated, the authors’ point of views are presented and the solution of the problem of the bibliography functions classification
A. V. Sokolov, T. F. Berestova
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2014 French version available in IDRC Digital Library: Culture de planification fondée sur des données probantes : processus adopté pour la mise en oeuvre de l'initiative NEHSI; démarche de l'initiative Données probantes et systèmes de santé au Nigeria ...
IDRC. Nigeria Evidence-based Health System Initiative (NEHSI)
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Component-Based Approach in Learning Management System Development
The paper describes component-based approach (CBA) for learning management system development. Learning object as components of e-learning courses and their metadata is considered.
Bule, Jekaterina +2 more
core
Component Approach to Software Development for Distributed Multi-Database System [PDF]
The paper deals with a component based approach for software development in a distributed environment for the database retrieval operations. A Core Component for a distributed multi-database system has been proposed.
Vijayakumar BALAKRISHNAN +2 more
core +1 more source