Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Peptide hormones in shaping root system architecture and environmental adaptation: Current advances and translational perspectives. [PDF]
Zhao X, Tan H, Li G, Xu Y, Ding Z, Yu Z.
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Lithuania's National Digital Health System Architecture, Evolution, and Lessons From a Centralized Approach Using Longitudinal Document Analysis: Descriptive National Case Study. [PDF]
Dapkutė A +9 more
europepmc +1 more source
System and software architectures
Lawrence Chung, Nary Subramanian
openaire +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Root system architecture modulates nitrogen uptake and use efficiency, influencing grain yield in rice. [PDF]
Bano Z, Kiran A, Imran A, Wakeel A.
europepmc +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
In order to facilitate teachers and students to quickly locate the required literature resources in the massive electronic literature, improve the efficiency of electronic literature resource utilization, and achieve personalized and accurate literature ...
HU Guoqiang
doaj
Effect of phosphorus deficiency on biomass and root system architecture in diverse <i>Medicago</i> accessions. [PDF]
Devabhakthini N +5 more
europepmc +1 more source

