Results 161 to 170 of about 12,384,515 (284)

Applying the major system change framework to evaluate implementation of rapid healthcare system change: a case study of COVID-19 remote home monitoring services. [PDF]

Implement Sci Commun
Walton H, Crellin N, Litchfield I, Sherlaw-Johnson C, Georghiou T, Massou E, Sidhu M, Tomini SM, Herlitz L, Ellins J, Ng PL, Fulop NJ.   +11 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Centering marginalized care: Home care cooperatives and system change. [PDF]

Health Aff Sch
Gusoff GM, Stepick L, Soriano-Versoza A, Kazda K.   +3 more
europepmc   +1 more source

From patient outcomes to system change: Evaluating the impact of VHA's implementation of the Whole Health System of Care. [PDF]

Health Serv Res, 2022
Bokhour BG, Hyde J, Kligler B, Gelman H, Gaj L, Barker AM, Douglas J, DeFaccio R, Taylor SL, Zeliadt SB.   +9 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Transformative capacities for navigating system change: a framework for sustainability research and practice. [PDF]

Sustain Sci
Orr CJ, Burch S.
europepmc   +1 more source

Can Labelling Create Transformative Food System Change for Human and Planetary Health? A Case Study of Meat. [PDF]

Int J Health Policy Manag, 2021
Parker C, Carey R, Haines F, Johnson H.
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Practical strategies for achieving system change in the US: lessons and insights from the CONQUEST quality improvement programme. [PDF]

Prim Health Care Res Dev
Evans A, VanWyk J, Kerr M, Couper A, Pace WD, Tarabichi Y, Pullen R, Pollack M, Drummond MB, Ohar J, Meldrum C, Han MK, Kaplan A, Winders T, Wisnivesky J, Make B, Federman A, Carter V, Lang K, Mapel D, Hanania NA, Stolz D, Martinez FJ, Price D.   +23 more
europepmc   +1 more source

Beyond Received Wisdom and Authorised Accounts: What Knowledge Is Needed to Avoid Repeating History? Comment on "'Attending to History' in Major System Change in Healthcare in England: Specialist Cancer Surgery Service Reconfiguration". [PDF]

Int J Health Policy Manag, 2023
Martin GP.
europepmc   +1 more source