Results 81 to 90 of about 29,946,329 (341)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Online Deterministic 3D Trajectory Generation for Electric Vertical Take-Off and Landing Aircraft

Aerospace
The use of non-piloted eVTOL aircraft in non-segregated airspace requires reliable and deterministic automatic flight guidance systems for the aircraft to remain predictable to all the users of the airspace and maintain a high level of safety.
Zoe Mbikayi, Agnes Steinert, Dominik Heimsch, Moritz Speckmaier, Philippe Rudolph, Hugh Liu, Florian Holzapfel   +6 more
doaj   +1 more source

Turbulence in the highly restricted dynamics of a closure at second order: comparison with DNS

, 2014
S3T (Stochastic Structural Stability Theory) employs a closure at second order to obtain the dynamics of the statistical mean turbulent state. When S3T is implemented as a coupled set of equations for the streamwise mean and perturbation states ...
Constantinou, Navid C., Farrell, Brian F., Ioannou, Petros J., Jiménez, Javier, Lozano-Durán, Adrian, Nikolaidis, Marios-Andreas   +5 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Witness for initial system-environment correlations in open system dynamics

, 2010
We study the evolution of a general open quantum system when the system and its environment are initially correlated. We show that the trace distance between two states of the open system can increase above its initial value, and derive tight upper ...
Breuer H. P., Breuer H. P., E.-M. Laine, H.-P. Breuer, Henderson L., J. Piilo, Li C.-F., Lindblad G., Nielsen M. A., Rodríguez-Rosario C. A.   +9 more
core   +1 more source

New slip control system considering actuator dynamics [PDF]

, 2015
A new control strategy for wheel slip control, considering the complete dynamics of the electro-hydraulic brake (EHB) system, is developed and experimentally validated in Cranfield University's HiL system.
Assadian, Francis, Soltani, Amirmasoud
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Quantum Dynamics of a Bulk-Boundary System

, 2004
The quantum dynamics of a bulk-boundary theory is closely examined by the use of the background field method. As an example we take the Mirabelli-Peskin model, which is composed of 5D super Yang-Mills (bulk) and 4D Wess-Zumino (boundary).
't Hooft, Akihiro Murayama, Appelquist, Appelquist, Barbieri, Bergshoeff, Callan, Coleman, DeWitt, Faddeev, Freund, Goldberger, Hebecker, Hořava, Ichinose, Ichinose, Ichinose, Ichinose, Ichinose, Ichinose, Ichinose, Ichinose, Ichinose, Ichinose, Ichinose, Jack, Jansen, Kaplan, Miller, Miller, Mirabelli, Murayama, Polyakov, Polyakov, Randall, Randall, Shamir, Shoichi Ichinose, Weinberg, Wess, West   +40 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Generalization of Geyer’s commutation relations with respect to the orthogonal group in even dimensions

European Physical Journal C: Particles and Fields, 2020
A connection between the deformed Duffin–Kemmer–Petiau (DKP) algebra and an extended system of the parafermion trilinear commutation relations for the creation and annihilation operators $$a^{\pm }_{k}$$ a k ± and for an additional operator $$a_{0}$$ a 0
Yu. A. Markov, M. A. Markova
doaj   +1 more source