Results 101 to 110 of about 32,200,596 (338)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2006 This is a terse review of recent results on isochronous dynamical systems, namely systems of (first-order, generally nonlinear) ordinary differential equations (ODEs) featuring an open set of initial data (which might coincide with the entire set of all initial data), from which emerge solutions all of which are completely periodic (i.e ...
openaire +6 more sources
Ocean dynamics of outer solar system satellites
, 2019 Ocean worlds are prevalent in the solar system. Focusing on Enceladus, Titan, Europa, and Ganymede, I use rotating convection theory and numerical simulations to predict ocean currents and the potential for ice-ocean coupling.
Soderlund, Krista
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frequency-Dependent Bouc–Wen Modeling of Magnetorheological Damper Using Harmonic Balance Approach
ActuatorsMagnetorheological dampers (MRDs) are of great interest in engineering due to their continuously adjustable damping characteristics. Accurate models are essential for optimizing MRDs and analyzing system dynamics.
Ruijing Qian +5 more
doaj +1 more source
Simulation of Adhesive Contact of Soft Microfibrils
Lubricants, 2020 Adhesive contact between a flat brush structure with deformable microfibrils and an elastic half space is numerically simulated. The stiffness of pillars is modeled by linear springs.
Xin He, Qiang Li, Valentin L. Popov
doaj +1 more source
Dynamical systems theory for music dynamics
Chaos: An Interdisciplinary Journal of Nonlinear Science, 1995 We show that, when music pieces are cast in the form of time series of pitch variations, the concepts and tools of dynamical systems theory can be applied to the analysis of temporal dynamics in music. (i) Phase space portraits are constructed from the time series wherefrom the dimensionality is evaluated as a measure of the global dynamics of each ...
Boon, Jean-Pierre, Decroly, O.
openaire +3 more sources
Repeated interactions in open quantum systems
, 2013 Analyzing the dynamics of open quantum systems has a long history in mathematics and physics. Depending on the system at hand, basic physical phenomena that one would like to explain are, for example, convergence to equilibrium, the dynamics of quantum ...
Bruneau, Laurent +2 more
core +4 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source