Results 121 to 130 of about 28,979,637 (350)

Blind-Matched Filtering for Speech Enhancement with Distributed Microphones

open access: yesJournal of Electrical and Computer Engineering, 2012
A multichannel noise reduction and equalization approach for distributed microphones is presented. The speech enhancement is based on a blind-matched filtering algorithm that combines the microphone signals such that the output SNR is maximized.
Sebastian Stenzel, Jürgen Freudenberger
doaj   +1 more source

An Exploration of the System Dynamics Field: A Model-Based Policy Analysis

open access: yes, 2014
This report presents a first look study at the field of System Dynamics. The objective of the study is to perform a model-based policy analysis in order to investigate the future advancement of the System Dynamics field.
Rose, A.C. (author), Rose, A.C.
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Essential Skills for System Dynamics Practitioners: A Delft University of Technology Perspective

open access: yes, 2010
There is little consensus on the skills set required of a system dynamics practitioner. In this paper we use the teaching approach and learning goals of the system dynamics courses at the Delft University of Technology as a starting point to explore the ...
Meyers, W.K.   +9 more
core  

System Dynamics Modelling and System Analysis Applied in Complex Research Projects - the Case of VALUMICS

open access: yes, 2018
VALUMICS is a Horizon 2020 project funded by the European Commission (2017-2021). The project structure is highly integrated and transdisciplinary, building on the expertise of over 30 specialists in various fields of research including knowledge ...
Gudbrandsdottir, Ingunn Yr   +8 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Influenza A(H1N1)v Pandemic: An Exploratory System Dynamics Approach

open access: yes, 2010
This paper presents a small exploratory System Dynamics model related to the dynamics of the 2009 flu pandemic, also known as the Mexican flu, swine flu, or A(H1N1)v.
Hamarat, C. (author)   +3 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Making System Dynamics Cool II: New Hot Teaching and Testing Cases of Increasing Complexity

open access: yes, 2010
This follow-up paper presents several actual cases for testing and teaching System Dynamics. The cases were developed between April 2009 and January 2010 for the Introductory System Dynamics courses at Delft University of Technology in the Netherlands ...
Pruyt, E. (author), Pruyt, E.
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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