Results 111 to 120 of about 28,979,637 (350)

Making System Dynamics Cool? Using Hot Testing & Teaching Cases

, 2009
This paper deals with the use of ‘hot’ real-world cases for both testing and teaching purposes such as in the Introductory System Dynamics course at Delft University of Technology in the Netherlands.
Pruyt, E. (author), Pruyt, E.
core  

Cybersecurity dynamics in software development environment. What system traps do exist?

, 2020
Increasing dependency on information technology and an increasing number of cyber-attacks give rise to concerns about secure software development methods.
von Kutzschenbach, Michael, Zeijlemaker, Sander   +1 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Launch dynamics modeling and simulation of box-type multiple launch rocket system considering plane clearance contact

Defence Technology
As the performance of the box-type multiple launch rocket system (BMLRS) improves, its mechanical structures, particularly the plane clearance design between the slider on the rocket and the guide inside the launch canister, have grown increasingly ...
Jinxin Tang, Guoping Wang, Genyang Wu, Yutian Sun, Lilin Gu, Xiaoting Rui   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A system dynamics approach towards nearly zero energy districts

The transition to near-zero energy districts is shaped by a complex interplay of stakeholder interests, technological complementarities, and market dynamics.
Zapata Riveros, Juliana, Ulli-Beer, Silvia   +1 more
core  

An introduction to system dynamics

, 2016
This chapter presents the important concepts underlying the system dynamics modeling method. Following an initial definition of the term model, a summary of a successful system dynamics intervention is described.
Duggan, Jim, Jim Duggan
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Wavelet-based high order spectrum for local damage diagnosis of gears

Mechanics & Industry
Gears play an important role in transmission systems, allowing for high performance in terms of load capacity and efficiency. Common failures, such as spalling and pitting of gear teeth, can occur as a result of contact fatigue, excessive load, or sudden
Zhu Rui, Mousmoulis George, Gryllias Konstantinos   +2 more
doaj   +1 more source