Results 41 to 50 of about 20,853,741 (308)

The use of system dynamics group model building for analysing event causality within the nuclear industry [PDF]

open access: yes, 2010
Currently the most frequently used tools for investigating and learning from industrial accidents are based on linear, reductionist models of event causality.
Carhart, NJ, Yearworth, M
core  

An Approach to Improving the 4DEnVar‐Initialized Deterministic Prediction Skill for Global Weather

open access: yesGeophysical Research Letters
Global deterministic numerical weather predictions (DNWPs) initialized from the ensemble mean analysis of four‐dimensional ensemble‐variational (4DEnVar) data assimilation are usually worse than those initialized by four‐dimensional variational (4DVar ...
Shujun Zhu   +14 more
doaj   +1 more source

Towards Youth Mental Health System Reform: An Evaluation of Participatory Systems Modelling in the Australian Capital Territory

open access: yesSystems, 2023
Australia’s mental health system is failing young people. Calls for accountability, strategic long-term policy planning, and regional leadership have been identified as solutions to guide mental health reform.
Grace Yeeun Lee   +19 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Applications of system dynamics modelling to computer music [PDF]

open access: yes, 2000
Based on a composer's psycho-acoustic imagination or response to music, system dynamics modelling and simulation tools can be used as a scoring device to map the structural dynamic shape of interest of computer music compositions.
IAN WHALLEY, Whalley, Ian
core   +1 more source

Modelling of Institutional Capacity within Study of Energy Transition Dynamics

open access: yesEnvironmental and Climate Technologies, 2021
Institutional capacity is enabling environment for interactions between individuals and organizations. Understanding the changes required regarding the institutional capacity is needed to remove barriers and stimulate transition to sustainable energy ...
Farenhorste-Mikane Ieva   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Contribution to the Development of Simulation Model of Ship Turbine

open access: yesMATEC Web of Conferences, 2015
Simulation modelling, performed by System Dynamics Modelling Approach and intensive use of computers, is one of the most convenient and most successful scientific methods of analysis of performance dynamics of nonlinear and very complex natural technical
Božić Ratko   +2 more
doaj   +1 more source

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