Results 171 to 180 of about 24,380,822 (306)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Dataset for system identification of an automated self-inflating bag resuscitator under varying test-lung mechanics. [PDF]

Data Brief
Phan TD, Truong CT, Nguyen HH, Duong VT, Nguyen TT.   +4 more
europepmc   +1 more source

Corrigendum: Sparse system identification of leptin dynamics in women with obesity. [PDF]

Front Endocrinol (Lausanne), 2022
Amin MR, Pednekar DD, Azgomi HF, van Wietmarschen H, Aschbacher K, Faghih RT.   +5 more
europepmc   +1 more source

Development and Implementation of a Mandatory Animal Identification System: The Canadian Experience [PDF]

This article provides a brief history of the animal identification (ID) system that previously existed in Canada along with details on efforts to ‘‘reidentify’’ the country’s cattle herd. The current state of ID for various species is summarized, and the
Carlberg, Jared G.
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Correction: Retrieving interpretability to support vector machine regression models in dynamic system identification. [PDF]

Front Artif Intell
Pena-Campos J, Patino D, Ocampo-Martinez C, Ramos-Fernández JC, Salas-Brown M, Caicedo A.   +5 more
europepmc   +1 more source

System identification: a feasible, reliable and valid way to quantify upper limb motor impairments. [PDF]

J Neuroeng Rehabil, 2023
van de Ruit M, van der Velden LL, Onneweer B, Benner JL, Haarman CJW, Ribbers GM, Selles RW.   +6 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Aberrant hepatic glycogenolysis and elevated insulin clearance can lead to major glucose irregularities in type 2 diabetes: insights from system identification. [PDF]

Front Physiol
Wang C, Kanaley JA, Chen J, Tan J.
europepmc   +1 more source

Automated crystal system identification from electron diffraction patterns using multiview opinion fusion machine learning. [PDF]

Proc Natl Acad Sci U S A, 2023
Chen J, Zhang H, Wahl CB, Liu W, Mirkin CA, Dravid VP, Apley DW, Chen W.   +7 more
europepmc   +1 more source