Results 171 to 180 of about 2,620,504 (318)

[Identification of compartmental systems].

Iyo denshi to seitai kogaku. Japanese journal of medical electronics and biological engineering, 1985
MAEDA, Hajime, KODAMA, Shinzo
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

System identification: a feasible, reliable and valid way to quantify upper limb motor impairments. [PDF]

J Neuroeng Rehabil, 2023
van de Ruit M, van der Velden LL, Onneweer B, Benner JL, Haarman CJW, Ribbers GM, Selles RW.   +6 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Corrigendum: Sparse system identification of leptin dynamics in women with obesity. [PDF]

Front Endocrinol (Lausanne), 2022
Amin MR, Pednekar DD, Azgomi HF, van Wietmarschen H, Aschbacher K, Faghih RT.   +5 more
europepmc   +1 more source

On Identification of Biological Systems.

, 2014
System identification finds nowadays application in various areas of biological research as a tool of empiric mathematical modeling and model individualization. A fundamental challenge of system identification in biology awaits in the form of response variability.
openaire   +2 more sources

Particle Filters for System Identification of State-Space Models Linear in Either Parameters or States

, 2003
The potential use of the marginalized particle filter for nonlinear system identification is investigated. The particle filter itself offers a general tool for estimating unknown parameters in non-linear models of moderate complexity, and the basic trick
Schön, Thomas,, Gustafsson, Fredrik,
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A System Identification Approach to Motion Model Based on Full-Scale Ship Maneuvering Data. [PDF]

Sensors (Basel)
Tian Y, Tian W, Zhang K, Hua L, Wen J, Zhu F.   +5 more
europepmc   +1 more source

Automated crystal system identification from electron diffraction patterns using multiview opinion fusion machine learning. [PDF]

Proc Natl Acad Sci U S A, 2023
Chen J, Zhang H, Wahl CB, Liu W, Mirkin CA, Dravid VP, Apley DW, Chen W.   +7 more
europepmc   +1 more source